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Article
Open AccessTy** of inflammatory lesions of the pituitary
Inflammatory pituitary lesions account for 1.8% of all specimens from the German Pituitary Tumor Registry. They occure in 0.5% of the autoptical specimens and in 2.2% of the surgical cases. Women are significa...
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Article
Mit Akromegalie assoziierte Veränderungen der Nasenschleimhäute
Die Akromegalie ist eine seltene Erkrankung, die durch ein wachstumshormon- (HGH-)produzierendes Hypophysenadenom verursacht wird. Symptome wie eine Größenzunahme der Hände und Füße, des Kiefers mit Verbreiter...
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Article
Immunohistochemical Localisation of Cytokeratins in Craniopharyngioma
Background. Although craniopharyngiomas have been examined in several microscopical studies to date, immunohistochemical analysis has not been sufficient.
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Article
Transsphenoidal Cephaloceles in Adults. A Report of Two Cases and Review of the Literature
¶ Transsphenoidal cephalocele rarely occurs in adults. We describe two adult cases with transsphenoidal cephaloceles. The first case was a 53-year-old female who presented with spontaneous cerebrospinal fluid ...
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Article
Lymphocytic hypophysitis with central diabetes insipidus and consequent panhypopituitarism preceding a multifocal, intracranial germinoma in a prepubertal girl
We report the clinical course of a prepubertal girl with central diabetes insipidus (DI) and consequent panhypopituitarism evolving over a period of 10 years due to lymphocytic hypophysitis and subsequent ger...
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Article
Komibinierte neuronale und endokrine Tumoren der Sellaregion
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Chapter and Conference Paper
Persistent and Recurrent Hypercortisolism After Transsphenoidal Surgery for Cushing’s Disease
After transnasal operations in Cushing’s syndrome persisting hypercortisolism either due to negative pituitary exploration or due to subtotal tumor removal, and recurrence of the disease after successful surge...
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Article
Combined sellar gangliocytoma and pituitary adenoma in acromegaly or Cushing's disease
Three cases of a composite sellar tumour composed of a gangliocytoma and an adenoma are presented. Two patients who showed acromegaly and hyperprolactinaemia had a gangliocytoma and a growth hormone (GH)-prola...
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Article
The anterior pituitary lobe in patients with cystic craniopharyngiomas: Three cases of associated lymphocytic hypophysitis
Specimens of the anterior pituitary lobe were investigated histologically in 28 craniopharyngioma patients operated on transsphenoidally. The pituitary glands in 3 patients revealed lymphocytic invasion giving...
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Article
PHYSICAL AND ENDOCRINE FINDINGS IN CUSHING'S DISEASE OF CHILDREN TREATED BY TRANSSPENOIDAL OPERATION
Symptoms of Cushing's disease are develop** faster and more characteristically in children than in older patients. This study analizes physical and endocrine findings establishing the diagnosis of pituitary ...
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Article
The choice of treatment after incomplete adenomectomy in acromegaly: Proton- versus highvoltage radiation
The authors report the results of a study designed to compare the effectiveness of two different types of radiation in patients with acromegaly where surgical therapy had failed to normalize growth hormone (GH...
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Chapter
Chirurgische Therapie der Hyperprolaktinämie
Die Lage der Hypophyse in der Mitte der Schädelbasis und die unterschiedliche Ausdehnung raumfordernder Prozesse bestimmt die chirurgischen Möglichkeiten bei Raumforderungen mit Hyperprolaktinämie.
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Article
Corticotropin releasing hormone in plasma of patients with Cushing's disease
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Article
Aspects of personality in patients with pituitary adenomas
In 24 patients suffering from pituitary tumours, aspects of personality as covered by the FPI (Freiburger Personality Inventory), the Gie\en test and the STAI (State-Trait-Anxiety Inventory) were investigated ...
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Article
Transnasal surgery in the treatment of craniopharyngiomas
The results of transnasal-transsphenoidal surgery in 31 patients with craniopharyngioma are evaluated. To assess the value of transnasal surgery in cases with visual impairment, the results are compared to cas...
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Article
Carpal tunnel syndrome and acromegaly
50 patients with acromegaly and carpal tunnel syndrome have been examined electrophysiologically before and after transnasal operation of the pituitary adenoma. 32 of the 50 patients (64%) had symptoms of carp...
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Article
Inconsistent stimulation of plasma ACTH through corticotropin-releasing factor in a patient with central Cushing's disease due to pituitary adenoma
Three uncommon findings were observed in a case of Cushing's disease due to macroadenoma: no suppression of plasma ACTH during an 8-mg dexamethasone test, a negative corticotropin-releasing factor test, and a ...
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Article
Tumour ploidy in DNA histograms of pituitary adenomas
DNA analysis was performed by flow cytometry (FCM) in 59 cases of different types of pituitary adenomas who underwent microsurgery and were actively followed over a period of 3–6 years. Aneuploid DNA patterns ...
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Article
Cushing's disease due to an unusually large adenoma of the pituitary gland in infancy
We report an 18-month-old girl with Cushing's disease caused by a large adenoma of the pituitary gland. Tumour size and extension were determined by X-ray, CT-scan and angiographic studies. The endocrinologica...
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Article
Pituitary hyperplasia
Surgical specimens of 15 normal and 106 para-adenomous anterior pituitaries were studied immunocytochemically and in part electron microscopically for the presence of hyperplasia. GH cell hyperplasia was found...
