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    Article

    Cytotoxicity of chloral-derived β-carbolines is not specific towards neuronal nor dopaminergic cells

    β-Carbolines structurally related to the selective dopaminergic neurotoxin 1-methyl-4- phenylpyridinium (MPP+) may contribute to dopaminergic neurodegeneration in Parkinson’s disease. The chloral-derived mammalia...

    A. Storch, Y.-I. Hwang, G. Bringmann, D. Feineis, S. Ott in Journal of Neural Transmission (2006)

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    Progressive Neurodegeneration of the Dopaminergic system and Inhibition of the Complex I Induced by the Chloral-Derived Tetrahydro-β-Carboline TaClo

    TaClo (1-trichloromethyl-1,2,3,4-tetrahydro-β-carboline) appears to be a neurotoxic drug able to induce a slow develo** degeneration of dopamine neurons. This is indicated from measurements of the apomorphin...

    K.-H. Sontag, C. Heim, T. A. Sontag, W. Kolasiewicz, W. Clement in The Basal Ganglia V (1996)

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    Abstracts Second Congress of the European Society for Clinical Neuropharmacology

    Y. Agid, T. Arendt, U. Gärtner, M. Holzer in Journal of Neural Transmission / General S… (1995)