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Article
Malignant lymphoma of true histiocytic origin: Histiocytic Sarcoma
Ten tumors of true histiocytic origin (Histiocytic Sarcoma) are presented. The tumor cells were identified as histiocytes by immunological, cytochemical and ultrastructural criteria (cytoplasmic lysozyme activ...
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Article
Secreting peritoneal mesothelioma
A 29 year old woman, living in an area with a high level of asbestos exposure, developed the clinical features of peritoneal mesothelioma. The quantitative cytological features differed from those of other mes...
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Article
Hypomelanotic macules in tuberous sclerosis
Hypomelanotic macules of the skin in tuberous sclerosis (TS) are caused by a complex process, involving the synthesis and maturation of melanosomes. A quantitative method was developed to investigate the matur...
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Chapter and Conference Paper
Primary “Reticulum Cell Sarcoma” of the Skin:High Frequency of True Histiocytic Lymphoma (Histiocytic Sarcoma)
From 12 patients with primary reticulum cell sarcoma (large cell sarcoma) of the skin, the biopsy specimens were reviewed and additional enzyme histochemical, immunologic and ultrastructural techniques were ap...
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Chapter
Dendritic Reticulum Cell Sarcoma: A Rare Tumor of the Follicular Compartment
Recent developments in immunology have revealed that non-Hodgkin lymphomas may be considered as neoplastic counterparts of the reactions that normally take place after antigenic challenge in special compartmen...
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Article
Epidermal Langerhans cells in erythrokeratodermia variabilis
The distribution of epidermal Langerhans cells (LC) in erythrokeratodermia keratodermia variabilis (EKV) was investigated using enzyme-histochemical (ATPase) and immunohistochemical (anti-T6 and anti-HLA-Dr) t...
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Article
Cholescintigraphy with99mTc-diethyl-IDA for the detection of rejection of auxiliary liver transplants in pigs
In 15 pigs an auxiliary liver was transplanted and cholescintigraphy with99mTc-diethyl-IDA was performed to study the function of the livers separately. Serial scintigraphy of the recipient and donor liver was pe...
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Chapter
Histopathological Aspects of Dysplastic Nevi
A dysplastic nevomelanocytic nevus (DN) can be defined as a localized proliferation of melanocytes with cytological and architectural atypia. Synonyms for DN used in the literature include B-K mole, atypical m...
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Chapter
Histopathological and Cytopathological Aspects of Focal Liver Lesions
Focal liver lesions may be caused by tumor-like conditions, primary benign tumors, primary malignant tumors and tumor metastases. It is important to note that not only metastasis but also other conditions may ...
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Chapter
Immunohistopathological Aspects of Cutaneous Melanoma and Precursor Lesions
The presence of particular cellular chemical constituants can be demonstrated immunohistologically by visualizing the binding of specific antibodies to the constituants (antigens) in tissue sections. The natur...
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Article
Effective d-penicillamine treatment of an early diagnosed patient with Wilson's disease
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Chapter
Differential Diagnosis of Metastatic Lesions in the Lung
Focal lung lesions may consist of tumor-like conditions,primary benign tumors, primary malignant tumors or tumor metastases. Tumor-like conditions that may mimic primary lung cancer or metastatic cancer in the...
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Chapter
Class II HLA Antigens in Benign and Malignant Lesions of Melanocytic Origin
Following the unexpected detection of immunologically functional class II HLA antigens on melanoma cells in long–term culture [1, 2], several investigators have analyzed the expression of these antigens by sur...
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Article
Expression of class I and class II HLA antigens in primary and metastatic melanoma: Relation to prognosis
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Article
Expression of HLA antigens in paraffin sections of uveal melanomas
Expression of histocompatibility (HLA) antigens on tumor cells may influence the recognition of these tumor cells by the immune system. Immunological recognition may influence tumor growth and patient survival.
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Chapter
Case 4: Type of Small-Cell Undifferentiated Cancer?
A 34-year old woman was admitted to an outside hospital because of acute loss of vision of the right eye. Conventional X-ray examination revealed an irregular osteolytic defect of the right maxilla with marked...
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Chapter
Case 3: Type of Sarcoma?
A 18-year-old woman was admitted to the hospital because of pain in the left upper leg. X-ray examination revealed an irregular osteolytic defect in the distal femur with extraosseal extension. A differential ...
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Chapter
Case 5: Type of Epitheloid and Clear Cell Cancer?
A 80-year old woman was admitted to the hospital because of pain in the left hip. X-ray examination revealed an irregular osteolytic defect in the acetabulum with marked extraosseal extension. A differential d...
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Chapter
Monoclonal Antibodies Recognizing Melanoma-Associated Antigens.
Cutaneous melanoma accounts for roughly 1% of cancers in the United States (1). It has been reported repeatedly that its incidence in western countries is rising rapidly (1). Accordingly, its mortality is risi...
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Chapter and Conference Paper
Melanoma Immunology
There have been major advances in the understanding of immunological processes in melanoma and in their application to the diagnosis and treatment of this cancer since the last World Congress of Dermatology. T...
