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  1. Article

    Open Access

    Lumbar disc extrusions reduce faster than bulging discs due to an active role of macrophages in sciatica

    This retrospective observational histological study aims to associate the size and type of disc herniation with the degree of macrophage infiltration in disc material retrieved during disc surgery in patients ...

    N. Djuric, X. Yang, A. el Barzouhi, R. Ostelo, S. G. van Duinen… in Acta Neurochirurgica (2020)

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  2. No Access

    Article

    Inclusion body myositis

    The clinical features of inclusion body myositis (IBM) were of minor importance in the design of consensus diagnostic criteria, mainly because of controversial views on the specificity of signs and symptoms, a...

    U. A. Badrising, M. L. C. Maat-Schieman, J. C. van Houwelingen… in Journal of Neurology (2005)

  3. No Access

    Article

    Age-related plaque morphology and C-terminal heterogeneity of amyloid β in Dutch-type hereditary cerebral hemorrhage with amyloidosis

    The evolvement of amyloid β (Aβ) deposition in the frontal cerebral cortex of 24 patients of increasing age with Dutch-type hereditary cerebral hemorrhage with amyloidosis (HCHWA-D) was studied using end-spec...

    M. L. C. Maat-Schieman, H. Yamaguchi, S. G. van Duinen, R. Natté… in Acta Neuropathologica (2000)

  4. No Access

    Article

    CNS involvement in primary Sjögren’s syndrome: a case with a clue for the pathogenesis

    M. J. Rood, J. J. G.M. Verschuuren, S. G. van Duinen… in Journal of Neurology (2000)

  5. No Access

    Article

    Numerous and widespread α-synuclein-negative Lewy bodies in an asymptomatic patient

    Lewy bodies (LB) and pale bodies (PB), their putative precursors, can be found in a spectrum of diseases characterized by parkinsonism and/or dementia. Furthermore, LB are occasionally observed in some other ...

    S. G. van Duinen, Gert-Jan Lammers, Marion L. C. Maat-Schieman… in Acta Neuropathologica (1999)

  6. No Access

    Chapter

    Intravascular Ultrasound Combined with Raman Spectroscopy

    The structure and chemical composition of atherosclerotic plaques appear to determine whether a plaque will rupture, resulting in an acceleration of clinical symptoms. Previous studies showed that Raman spectr...

    T. J. Römer, J. F. Brennan III… in Spectroscopy of Biological Molecules: Mode… (1997)

  7. No Access

    Article

    Hereditary cerebral hemorrhage with amyloidosis (Dutch): a model for congophilic plaque formation without neurofibrillary pathology

    Plaque-like lesions and amyloid angiopathy were investigated in the frontal cerebral cortex of four patients with hereditary cerebral hemorrhage with amyloidosis (Dutch) (HCHWA-D), using immunohistochemical [a...

    M. L. C. Maat-Schieman, C. M. Radder, J. Haan, R. A. C. Roos… in Acta Neuropathologica (1994)

  8. No Access

    Article

    Morphology of cerebral plaque-like lesions in hereditary cerebral hemorrhage with amyloidosis (Dutch)

    We studied the presence and morphology of plaque-like lesions in the frontal cortex of six patients, aged 40 to 76 years, with hereditary cerebral hemorrhage with amyloidosis — Dutch type (HCHWA-D), using β/A4...

    M. L. C. Maat-Schieman, S. G. van Duinen, J. Haan, R. A. C. Roos in Acta Neuropathologica (1992)

  9. No Access

    Chapter

    Pathological Changes in Hereditary Cerebral Hemorrhage with Amyloidosis — Dutch Type

    Neuropathological findings in hereditary cerebral hemorrhage with amyloidosis — Dutch type are described.

    R. A. C. Roos, J. Haan, M. L. C. Maat-Schieman… in Amyloid and Amyloidosis 1990 (1991)

  10. No Access

    Article

    Monoclonal antibodies in detection of choroidal melanoma

    Three monoclonal antibodies (MoAbs) prepared against cutaneous melanomas were tested against one group of 12 choroidal melanomas with indirect immunofluorescence in frozen sections. A fourth MoAb was tested in...

    P. J. Ringens, R. van Haperen, C. Vennegoor… in Graefe's Archive for Clinical and Experime… (1989)

  11. No Access

    Chapter

    Class II HLA Antigens in Benign and Malignant Lesions of Melanocytic Origin

    Following the unexpected detection of immunologically functional class II HLA antigens on melanoma cells in long–term culture [1, 2], several investigators have analyzed the expression of these antigens by sur...

    D. J. Ruiter, S. G. van Duinen, M. Tsujisaki, S. Ferrone in HLA Class II Antigens (1986)

  12. No Access

    Chapter

    Immunohistopathological Aspects of Cutaneous Melanoma and Precursor Lesions

    The presence of particular cellular chemical constituants can be demonstrated immunohistologically by visualizing the binding of specific antibodies to the constituants (antigens) in tissue sections. The natur...

    D. J. Ruiter, S. G. van Duinen, S. O. Warnaar in Cutaneous Melanoma and Precursor Lesions (1984)

  13. No Access

    Article

    Hypomelanotic macules in tuberous sclerosis

    Hypomelanotic macules of the skin in tuberous sclerosis (TS) are caused by a complex process, involving the synthesis and maturation of melanosomes. A quantitative method was developed to investigate the matur...

    D. J. Ruiter, S. G. van Duinen, A. C. B. Peters… in Archives of Dermatological Research (1981)