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  1. No Access

    Article

    Robotic iliopubic tract (r-IPT) repair: technique and preliminary outcomes of a minimally invasive tissue repair for inguinal hernia

    The iliopubic tract repair was first introduced by Nyhus in 1959, as an open non-mesh posterior preperitoneal repair for inguinal hernia. We have adapted this repair using a robotic approach to offer a minimal...

    D. Huynh, N. Fadaee, B. Al-Aufey, I. Capati, S. Towfigh in Hernia (2020)

  2. Article

    Open Access

    Durable targeting of B-lymphocytes in living mice

    Transfer to and enduring expression of genes in B cells has proved a vexing challenge. We report here a novel method for the specific and durable targeting of B lymphocytes in living mice. The method involves ...

    M. Cascalho, D. Huynh, A. R. Lefferts, L. Stein, T. Lanigan… in Scientific Reports (2018)

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  3. Article

    Open Access

    Whole-exome sequencing of cell-free DNA and circulating tumor cells in multiple myeloma

    Liquid biopsies including circulating tumor cells (CTCs) and cell-free DNA (cfDNA) have enabled minimally invasive characterization of many cancers, but are rarely analyzed together. Understanding the detectab...

    S. Manier, J. Park, M. Capelletti, M. Bustoros, S. S. Freeman… in Nature Communications (2018)

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  4. No Access

    Article

    The LIN28B/let-7 axis is a novel therapeutic pathway in multiple myeloma

    MYC is a major oncogenic driver of multiple myeloma (MM) and yet almost no therapeutic agents exist that target MYC in MM. Here we report that the let-7 biogenesis inhibitor LIN28B correlates with MYC expression ...

    S Manier, J T Powers, A Sacco, S V Glavey, D Huynh, M R Reagan, K Z Salem… in Leukemia (2017)

  5. No Access

    Article

    Phase I/II trial of everolimus in combination with bortezomib and rituximab (RVR) in relapsed/refractory Waldenstrom macroglobulinemia

    We examined the combination of the mammalian target of rapamycin inhibitor everolimus with bortezomib and rituximab in patients with relapsed/refractory Waldenstrom macroglobulinemia (WM) in a phase I/II study...

    I M Ghobrial, R Redd, P Armand, R Banwait, E Boswell, S Chuma, D Huynh, A Sacco… in Leukemia (2015)

  6. Article

    Intestinal adenoma formation and MYC activation are regulated by cooperation between MYB and Wnt signaling

    Aberrant Wnt signaling mediated by mutations affecting APC (adenomatous polyposis coli) or β-catenin initiates the majority of human colorectal cancers (CRC) and drives tumorigenesis through the activation of spe...

    D Ciznadija, R Tothill, M L Waterman, L Zhao, D Huynh… in Cell Death & Differentiation (2009)

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