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    Article

    Immune Checkpoint Inhibitors as Switch or Continuation Maintenance Therapy in Solid Tumors: Rationale and Current State

    First-line chemotherapy for many solid tumors is limited by toxicity. There is a growing interest in maintenance therapy as a strategy for prolonging the benefits of first-line therapy while minimizing toxicit...

    Petros Grivas, Bradley J. Monk, Daniel Petrylak, Martin Reck… in Targeted Oncology (2019)

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    Article

    The Rb-family protein p107 inhibits translation by a PDK1-dependent mechanism

    The Rb family of proteins, which consists of Rb, p107 and p130, are critical regulators of cell proliferation. In addition to their inhibitory effects on cell cycle progression, Rb-family proteins repress tran...

    Constantin Makris, Laure Voisin, Edith Giasson, Christopher Tudan… in Oncogene (2002)