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  1. No Access

    Chapter

    Solid state conformation of constrained Somatostatin analogs with high potency and specificity for the μ-opioid receptor

    Judith L. Flippen-Anderson, Jeffrey R. Deschamps… in Peptides Frontiers of Peptide Science (2002)

  2. No Access

    Chapter

    Solid state conformation of serine3 DPDPE

    Judith L. Flippen-Anderson, Jeffrey R. Deschamps… in Peptides for the New Millennium (2002)

  3. No Access

    Chapter

    First peptide-based system of rigid donor, rigid acceptor, and rigid interchromophore spacer: A conformational and photophysical study

    Claudio Toniolo, Fernando Formaggio, Marco Crisma… in Peptides Frontiers of Peptide Science (2002)

  4. No Access

    Article

    Conformational preferences of the potent dopamine reuptake blocker BTCP and its analogs and their incorporation into a pharmacophore model

    Molecular mechanics calculations using MM3-92 and ab initio quantum mechanical calculations using SPARTAN 5.0 were performed on the structurally similar PCP and BTCP, in which only the latter has a cocaine-lik...

    Mark Froimowitz, Kuo-Ming Wu, Jason Rodrigo… in Journal of Computer-Aided Molecular Design (2000)

  5. No Access

    Article

    The relationship between structure and activity among opioid peptides

    Since the discovery and isolation of the endogenous opioid peptides Leu- and Met-enkephalin, structural studies have been focused on deducing the bioactive conformation of the peptide ligands. Theoretically, l...

    Jeffrey R. Deschamps, Clifford George… in Letters in Peptide Science (1998)

  6. No Access

    Article

    The Relationship Between Structure and Activity Among Opioid Peptides

    Since the discovery and isolation of the endogenous opioid peptides Leu- and Met-enkephalin, structural studies have been focused on deducing the bioactive conformation of the peptide ligands. Theoretically, l...

    Jeffrey R. Deschamps, Clifford George… in Letters in Peptide Science (1998)

  7. No Access

    Article

    Crystal Structures of Analogs of threo-Methylphenidate

    The crystal structures of the chloride salts of five analogs of threo-methylphenidate have been obtained. Four of these have different substituents on the phenyl ring while the fifth is the ethyl ester of methylp...

    Mark Froimowitz, Kuo-Ming Wu, Clifford George, Don VanDerveer… in Structural Chemistry (1998)

  8. No Access

    Article

    X-ray crystallographic and molecular modeling studies of 1-(2,6-difluorobenzoyl)-5-(4-chlorophenyl)biuret

    Crystals of 1-(2,6-difluorobenzoyl)-5-(4-chlorophenyl)biuret (BFB), C15H10N3O3F2Cl, were grown by evaporation from an acetonitrile solution. Two polymorphs were obtained. The first polymorph (BFB1) crystallized i...

    Jeffrey R. Deschamps, Clifford George… in Journal of Chemical Crystallography (1998)

  9. No Access

    Article

    Crystallographic structure of a helical lipopeptaibol antibiotic analogue

    An X-ray diffraction analysis of the [Fmoc0,TOAC4,8, Leu-OMe11] analogue of thelipopeptaibol antibiotic trichogin A IV shows that the undecapeptide isfolded in a right-handed, mixed α/310-helix. The helicalmolecu...

    Marco Crisma, Vania Monaco, Fernando Formaggio… in Letters in Peptide Science (1997)

  10. No Access

    Article

    Crystallographic structure of a helical lipopeptaibol antibiotic analogue

    An X-ray diffraction analysis of the [Fmoc0, TOAC4,8, Leu-OMe11]analogue of the lipopeptaibol antibiotic trichogin A Iv shows that the undecapeptide is folded in a right-handed, mixed α/310-helix. The helical mol...

    Marco Crisma, Vania Monaco, Fernando Formaggio… in Letters in Peptide Science (1997)

  11. No Access

    Article

    Imidazolium chloride organophosphate antidotes

    The structures of four imidazolium oxime derivatives were solved by direct methods. These compounds have been shown to be effective in the treatmen of organophosphate poisoning. Despite substantial differences...

    Jeffrey R. Deschamps, Clifford George… in Journal of Chemical Crystallography (1997)

  12. No Access

    Article

    Distortions in nitramine substituted cubanes: The structures of N,N′-dinitro-1,4-diaminocubane, N,N′-dinitro-N,N′-(2-pyridyl)-1,4-diaminocubane, and 1,2,4,7-tetrakis(N-methoxycarbonylnitramino)cubane

    The structures of three nitramine substituted cubane molecules, N,N′-dinitro-1,4-diaminocubane (1), N,N′-dinitro-N,N′-(2-pyridyl)-1,4-diaminocubane (2), and 1,2,4,7-Tetrakis(N-methoxycarbonylnitramino)-cubane (3)...

    Ray J. Butcher, Richard D. Gilardi, Clifford George… in Journal of Chemical Crystallography (1996)

  13. No Access

    Article

    X-ray structures of the δ opioid antagonist TIPP and a protected derivative of the δ opioid antagonist ICI 174,864

    The solid state structures of two synthetic opioid peptides have been determined by X-ray single crystal analysis. The first X-ray structure is that of N,N-diallyl-(O-t-butyl)-Tyr-Aib-Aib-Phe-Leu-OMe (RTI02), a p...

    Judith L. Flippen-Anderson, Clifford George… in Letters in Peptide Science (1994)

  14. No Access

    Chapter

    Mixed-Ligand, Non-Nitrosyl Cu(II) Complexes as Potential Pharmacological Agents via NO Release

    Nitric oxide (NO) has recently been established as a key bioregulatory agent1. Its multifaceted nature has been demonstrated in vascular relaxation, antiplatelet action, macrophage induced cytostasis and cytotoxi...

    Danae Christodoulou, Chris M. Maragos, Clifford George… in Bioinorganic Chemistry of Copper (1993)

  15. No Access

    Article

    Iron(III) complexes of some thiosemicarbazones derived from 2-acetylpyridine, its 6-methyl derivative and itsN-oxide

    A series of iron(III) complexes of thiosemicarbazones derived from 2-acetylpyridine, 6-methyl-2-acetylpyridine and 2-acetylpyridineN-oxide have been prepared from Fe(ClO4)3 and FeCl3. All of the isolated solids h...

    Douglas X. West, Patricia M. Ahrweiler, Gözen Ertem… in Transition Metal Chemistry (1985)