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Open AccessUlcerating skin lesions from blastic plasmacytoid dendritic cell neoplasm responding to low-dose radiotherapy—a case report and literature review
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy that can manifest with skin nodules and erythematous plaques. In most cases BPDCN progresses rapidly, causing multiple skin...
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The Role of MR-Guided Radiation Therapy in the Management of Liver Malignancies
Radiation therapy (RT) has continued to be a mainstay of treatment for cancer, serving as either an alternative or adjunct to chemotherapy and surgery. While computerized tomography (CT) has traditionally been...
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Article
Open AccessIs consolidative thoracic radiotherapy of extensive-stage small cell lung cancer still beneficial in the era of immunotherapy? A retrospective analysis
Extensive-stage small cell lung cancer (ES-SCLC) carries a dismal prognosis. The benefit of consolidative thoracic radiotherapy (TR) after first-line chemoimmunotherapy with PD-L1 inhibitors in this setting re...
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Article
Open AccessA patterns of care analysis of hyperthermia in combination with radio(chemo)therapy or chemotherapy in European clinical centers
The combination of hyperthermia (HT) with radio(chemo)therapy or chemotherapy (CT) is an established treatment strategy for specific indications. Its application in routine clinical practice in Europe depends ...
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Rectal Cancer
Radiotherapy (RT) has been a cornerstone in the multimodal treatment for patients with locally advanced rectal cancer. For a long time, target volume delineation between radiation oncologists remained inhomoge...
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Article
Open AccessPostoperative complications and oncologic outcomes after multimodal therapy of localized high risk soft tissue sarcoma
Standard therapy for localized high-risk soft tissue sarcoma includes surgical resection and neoadjuvant or adjuvant radiation therapy (± chemotherapy and locoregional hyperthermia). No difference in oncologic...
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Article
Open AccessSimulation CT-based radiomics for prediction of response after neoadjuvant chemo-radiotherapy in patients with locally advanced rectal cancer
To report on the discriminative ability of a simulation Computed Tomography (CT)-based radiomics signature for predicting response to treatment in patients undergoing neoadjuvant chemo-radiation for locally ad...
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Article
Open AccessRadiotherapy planning parameters correlate with changes in the peripheral immune status of patients undergoing curative radiotherapy for localized prostate cancer
The influence of radiotherapy on patient immune cell subsets has been established by several groups. Following a previously published analysis of immune changes during and after curative radiotherapy for prost...
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Article
Correction to: Value of PET imaging for radiation therapy
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Article
Open AccessCorrection to: Innovative radiation oncology Together—Precise, Personalized, Human
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Open AccessInnovative radiation oncology Together – Precise, Personalized, Human
Scientific and clinical achievements in radiation, medical, and surgical oncology are changing the landscape of interdisciplinary oncology. The German Society for Radiation Oncology (DEGRO) working group of yo...
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International consensus recommendations on key outcome measures for organ preservation after (chemo)radiotherapy in patients with rectal cancer
Multimodal treatment strategies for patients with rectal cancer are increasingly including the possibility of organ preservation, through nonoperative management or local excision. Organ preservation strategie...
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Article
Open AccessStellenwert des 1,5-T-MR-Linearbeschleunigers für die primäre Therapie des Prostatakarzinoms
Der potenzielle Nutzen des verbesserten Weichteilkontrastes von MR-Sequenzen gegenüber der Computertomographie (CT) für die Radiotherapie des Prostatakarzinoms ist bekannt und führt zu konsistenteren und klein...
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Value of PET imaging for radiation therapy
This comprehensive review written by experts in their field gives an overview on the current status of incorporating positron emission tomography (PET) into radiation treatment planning. Moreover, it highlight...
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Article
Quality of life and fatigue before and after radiotherapy in breast cancer patients
Cancer-related fatigue (CRF) is a common side effect of cancer treatment, particularly in breast cancer patients. Over the past decade, the multimodal management of breast cancer has undergone several changes,...
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Article
Klinische Komplettremission beim Rektumkarzinom: Wann ist weniger mehr?
Nach neoadjuvanter Radiochemotherapie (RCT) wird bei 10–20 % der Patienten mit lokal fortgeschrittenem Rektumkarzinom eine pathologische Komplettremission nachgewiesen.
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Article
Organerhaltende Konzepte durch Radiochemotherapie: Wo stehen wir?
Nach neoadjuvanter Radiochemotherapie (RCT) wird bei 10–20 % der Patienten mit lokal fortgeschrittenem Rektumkarzinom eine pathologische Komplettremission nachgewiesen.
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Organerhalt beim Rektumkarzinom durch Radiochemotherapie
Nach neoadjuvanter Radiochemotherapie (RCT) wird bei 10–20 % der Patienten mit Rektumkarzinom im Operationspräparat eine pathologische Komplettremission nachgewiesen.
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Radiogenomics in head and neck cancer: correlation of radiomic heterogeneity and somatic mutations in TP53, FAT1 and KMT2D
Genetic tumour profiles and radiomic features can be used to complement clinical information in head and neck squamous cell carcinoma (HNSCC) patients. Radiogenomics imply the potential to investigate compleme...
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Rendezvous endoscopic recanalization for complete esophageal obstruction
Complete esophageal obstruction after (chemo)radiation for head and neck cancers is rare. However, inability to swallow one’s own saliva strongly inflicts upon quality of life. Techniques for endoscopic recana...