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Article
Open AccessDesign of a delivery vehicle chitosan-based self-assembling: controlled release, high hydrophobicity, and safe treatment of plant fungal diseases
Traditional pesticides are poorly water-soluble and suffer from low bioavailability. N-succinyl chitosan (NSCS) is a water-soluble chitosan derivative, has been recently used to encapsulate hydrophobic drugs to i...
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Article
Platelet-Derived Microvesicles Mediate Cardiomyocyte Ferroptosis by Transferring ACSL1 During Acute Myocardial Infarction
Acute myocardial infarction (AMI) is one of the critical health conditions often caused by the rupture of unstable coronary artery plaque, triggering a series of events, such as platelet activation, thrombus f...
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Article
Open AccessDevelopment of highly efficient and specific base editors in Actinobacillus succinogenes for enhancing succinic acid production
The production of bio-succinic acid (SA) from renewable feedstocks is a promising and sustainable approach to mitigating the high carbon emissions associated with the current energy crisis. Actinobacillus succino...
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Article
Open AccessThree novel leaderless bacteriocins have antimicrobial activity against gram-positive bacteria to serve as promising food biopreservative
Due to the detrimental effects of chemical preservatives, there has been an increasing demand for safer, healthier and natural bio-preservatives. Bacteriocins have attracted increasing interest because of thei...
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Article
Open AccessTranscriptome analysis of the production enhancement mechanism of antimicrobial lipopeptides of Streptomyces bikiniensis HD-087 by co-culture with Magnaporthe oryzae Guy11
The lipopeptides produced by Streptomyces bikiniensis have a significant inhibitory effect on Magnaporthe oryzae, but the low yield limits its application. In this study, the anti-M. oryzae activity of the broth ...
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Article
Microwave-assisted pyrolysis of phosphoric acid-activated Goldenberry peel powder biochar for enhancing the adsorption of trace beta-lactamase inhibitors
Novel efficient biochar of Goldenberry peels (GBPMW-H3PO4) was prepared through a microwave-assisted phosphoric acid activation method. It was characterized and used for removing two beta-lactamase inhibitors, su...
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Article
Open AccessApplication of lipid nanovesicle drug delivery system in cancer immunotherapy
Immunotherapy has gradually emerged as the most promising anticancer therapy. In addition to conventional anti-PD-1/PD-L1 therapy, anti-CTLA-4 therapy, CAR-T therapy, etc., immunotherapy can also be induced by...
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Article
Open AccessRecent advances of fluorescent biosensors based on cyclic signal amplification technology in biomedical detection
The cyclic signal amplification technology has been widely applied for the ultrasensitive detection of many important biomolecules, such as nucleic acids, proteins, enzymes, adenosine triphosphate (ATP), metal...
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Article
Open AccessChitosan oligosaccharide decorated liposomes combined with TH302 for photodynamic therapy in triple negative breast cancer
Triple negative breast cancer (TNBC) is an aggressive tumor with extremely high mortality that results from its lack of effective therapeutic targets. As an adhesion molecule related to tumorigenesis and tumor...
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Article
Open AccessLRP1-mediated pH-sensitive polymersomes facilitate combination therapy of glioblastoma in vitro and in vivo
Glioblastoma (GBM) is the most invasive primary intracranial tumor, and its effective treatment is one of the most daunting challenges in oncology. The blood–brain barrier (BBB) is the main obstacle that preve...
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Article
Open AccessEnhancement of polyhydroxyalkanoate production by co-feeding lignin derivatives with glycerol in Pseudomonas putida KT2440
Efficient utilization of all available carbons from lignocellulosic biomass is critical for economic efficiency of a bioconversion process to produce renewable bioproducts. However, the metabolic responses tha...
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Protocol
Plastid Transformation in Poplar: A Model for Perennial Trees
Poplar (Populus) is an important forest tree and considered model for perennial trees. Here we describe a method for poplar plastid transformation, which involves preparation of explants, vector construction, bio...
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Article
Genome-wide identification and functional analysis of the WDR protein family in potato
WD-repeat (WDR) proteins are highly abundant and participate in a seemingly wide range of interactions and cellular functions acting as scaffolding molecules. However, WDR identification in potato has not been...
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Article
Open AccessGenomic sequencing, genome-scale metabolic network reconstruction, and in silico flux analysis of the grape endophytic fungus Alternaria sp. MG1
Alternaria sp. MG1, an endophytic fungus isolated from grape, is a native producer of resveratrol, which has important application potential. However, the metabolic characteristics and physiological behavior of M...
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Article
Open AccessEffects of soybean meal fermented by L. plantarum, B. subtilis and S. cerevisieae on growth, immune function and intestinal morphology in weaned piglets
The present study compared the effects of soybean meal fermented by three different probiotics organisms with non-fermented soybean meal on growth performance, serum parameters, immune chemistry and intestinal...
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Article
Association of LIM Domain 7 Gene Polymorphisms and Plasma Levels of LIM Domain 7 with Dilated Cardiomyopathy in a Chinese Population
The aim of our study was to investigate the potential association of mRNA expression and plasma levels of the LIM domain 7 (LMO7) gene with the pathogenesis of dilated cardiomyopathy (DCM). Two SNPs of the LMO7 g...
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Article
Iron-manganese-magnesium mixed oxides catalysts for selective catalytic reduction of NO x with NH3
SCR activity at low temperature over iron oxide catalyst was prominently optimized by adding manganese and magnesium. Fe0.7Mn0.15Mg0.15O z (n(Mn)/[n(Fe)+n(Mn)+n(Mg)])=0.15 and n(...
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Article
NH3-SCR performance and characterization over magnetic iron-magnesium mixed oxide catalysts
A series of magnetic iron-magnesium mixed oxide catalysts (Fe1−x Mg x O z ) were synthesized via a novel coprecipitation...
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Chapter
Uptake and Accumulation of Engineered Nanomaterials and Their Phytotoxicity to Agricultural Crops
Rapidly expanding world population and dwindling arable land around the world demand innovative technologies to drastically enhance the global crop yield in the near future. The advancement in nanotechnology p...
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Chapter
Cell-Specific Aptamers for Molecular Imaging
Aptamers, single-stranded oligonucleotides, are an important class of molecular targeting ligands. Since their discovery, aptamers have been rapidly translated into bioanalytical practice. They have been appro...