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Article
TGF-β/SMAD Pathway Mediates Cadmium Poisoning-Induced Chicken Liver Fibrosis and Epithelial-Mesenchymal Transition
Cadmium(Cd) is a toxic heavy metal widely present in the environment, capable of accumulating in the liver and causing liver damage. In this study, the mechanism of cadmium-induced liver fibrosis in chickens w...
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Article
Structure-Preserving Recurrent Neural Networks for a Class of Birkhoffian Systems
In this paper, the authors propose a neural network architecture designed specifically for a class of Birkhoffian systems — The Newtonian system. The proposed model utilizes recurrent neural networks (RNNs) an...
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Article
Open AccessPrognostic value of oxidative stress-related genes in colorectal cancer and its correlation with tumor immunity
Oxidative stress (OS) plays an essential role in chronic diseases such as colorectal cancer (CRC). In this study, we aimed to explore the relation between oxidative stress-related genes and CRC prognosis and t...
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Article
Protective effects of maternal administration of total saponins of Codonopsis pilosula in the mice offspring following diarrhea: role of immune function, antioxidant function, and intestinal inflammatory injury
Total saponins of Codonopsis (TSC) are a kind of critical bioactive substances in Codonopsis, which have anti-inflammatory, antioxidant, anti-ulcer, immunomodulatory effects, and protective effects on ulcerative ...
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Article
Open AccessIron-based metal-organic framework co-loaded with buthionine sulfoximine and oxaliplatin for enhanced cancer chemo-ferrotherapy via sustainable glutathione elimination
Emerging ferroptosis-driven therapies based on nanotechnology function either by increasing intracellular iron level or suppressing glutathione peroxidase 4 (GPX4) activity. Nevertheless, the therapeutic strat...
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Article
Mesenchymal Stem Cell-Derived Exosomes are Effective for Radiation Enteritis and Essential for the Proliferation and Differentiation of Lgr5+ Intestinal Epithelial Stem Cells by Regulating Mir-195/Akt/β-Catenin Pathway
Radiation enteritis (RE) is a common complication of abdominal or pelvic radiotherapy, which when severe, could be life-threatening. Currently, there are no effective treatments. Studies have shown that mesenc...
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Article
The promoting effect of health education on medical treatment seeking behavior in the context of healthy China: based on the comparison of migrants and registered local residents
The migrants are the important participant and contributor in China's economic and social construction, but they still have many restrictions on their access to health services. This paper analyzes the differe...
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Chapter
Smart Education F5G All-Optical Network Solution
F5G empowers everything perception and web applications. Huawei F5G all-light park mainly adopts F5G passive optical local area network (POL) technology, with single-mode optical fiber as the medium, using 10G...
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Article
Open AccessEvaluation of the local decoupling of livestock and cropland in the Huang-Huai-Hai region
Decoupling livestock and cropland production at regional scale have poor resource-use efficiency and detrimental effects on environment in China. It is therefore necessary to identify the decoupled livestock a...
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Article
Selenium Deficiency Induces Autophagy in Chicken Bursa of Fabricius Through ChTLR4/MyD88/NF-κB Pathway
To explore the role of ChTLR4/MyD88/NF-κB signaling pathway on autophagy induced by selenium (Se) deficiency in the chicken bursa of Fabricius, autophagosome formation in the bursa of Fabricius was observed by...
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Article
Selenium Deficiency Causes Inflammatory Injury in the Bursa of Fabricius of Broiler Chickens by Activating the Toll-like Receptor Signaling Pathway
The aim of our study was to observe the effect of selenium (Se) deficiency on inflammatory injury in the bursa of Fabricius of broiler chickens and to determine the role of the Toll-like receptor (TLR)/myeloid...
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Article
Open AccessEffect of pyrene-induced changes in root activity on growth of Chinese cabbage (Brassica campestris L.), and the health risks caused by pyrene in Chinese cabbage at different growth stages
Polycyclic aromatic hydrocarbons (PAHs) pose a potential risk to ecological safety and human health. They have a range of effects on plant growth and there have been few reports on the health risks associated ...
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Article
Astragalus Polysaccharide Protects Against Cadmium-Induced Autophagy Injury Through Reactive Oxygen Species (ROS) Pathway in Chicken Embryo Fibroblast
Cadmium (Cd) is a harmful heavy metal pollutant, which can cause oxidative stress in the body and induce cell damage. Reactive oxygen species (ROS) is a general term for substances that contain oxygen and are ...
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Article
Genetic diversity in natural populations of Sorbus pohuashanensis based on EST-SSR markers
The natural population in S. pohuashanensis had a high-level genetic diversity and higher level genetic differentiation.
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Article
Selenium Deficiency via the TLR4/TRIF/NF-κB Signaling Pathway Leading to Inflammatory Injury in Chicken Spleen
The aim of the present study was to investigate the effect of selenium (Se) deficiency on the expression of the toll-like receptor (TLR) signal transduction pathway in the spleen of chickens and explore the re...
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Article
Open AccessAnalysis of chicken macrophage functions and gene expressions following infectious bronchitis virus M41 infection
Infectious bronchitis virus (IBV) is a pathogenic coronavirus with high morbidity and mortality in chicken breeding. Macrophages with normal biofunctions are essential for host immune responses. In this study,...
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Chapter
Curvilinear Mesh Adaptation
This paper aims at addressing the following issue. Assume a unit square: \(\varOmega = \{(x^1,x^2) \in [0,1] \times [0,1]\}\)
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Article
Open AccessCase study of an autoantibody panel for early detection of lung cancer and ground-glass nodules
Increasing lung cancer incidence in China with a high death rate due to late diagnosis highlights the need for biomarkers, such as panels of autoantibodies (AAbs), for prediction and early lung cancer diagnosi...
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Article
Molecular characterization and expression analysis of small heat shock protein 17.3 gene from Sorbus pohuashanensis (Hance) Hedl. in response to abiotic stress
Sorbus pohuashanensis, a native tree species in China that is distributed at high altitudes. However, the problem of adaptability when introducing S. pohuashanensis to low altitude areas has not been solved. sHSP...
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Article
Development and evaluation of EST-SSR markers in Sorbus pohuashanensis (Hance) Hedl. and their application to other Sorbus species
We developed and identified a new set of polymorphic EST-SSR markers in Sorbus pohuashanensis (Hance) Hedl. and generated an optimal sampling strategy.
