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Article
Skeletal muscle alterations indicate poor prognosis in cirrhotic patients: a multicenter cohort study in China
We aimed to determine the diagnostic criteria of myosteatosis in a Chinese population and investigate the effect of skeletal muscle abnormalities on the outcomes of cirrhotic patients.
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Article
Clinical phenotypes, molecular analysis, and outcomes of patients with Rosai-Dorfman disease
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Article
Social isolation does not alter the relationship between flexibility in metabolic rate and growth in grass carp (Ctenopharyngodon idella) under changing food availability
Growth and energy metabolism are highly flexible in fish species in response to food availability, and these two traits depend to some extent on the social rearing environment (e.g., isolated vs. group rearing). ...
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Article
Open AccessDirect arterial puncture for hemodialysis, a neglected but simple and valuable vascular access
The purpose of this study is to present the prevalence and effects of direct arterial puncture (DAP) for hemodialysis patients, and to introduce optimal option for the vascular access (VA) in certain hemodialy...
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Article
Application of Stable Strontium Isotope Geochemistry and Fluid Inclusion Microthermometry to Studies of Dolomitization of the Deeply Buried Cambrian Carbonate Successions in West-Central Tarim Basin, NW China
Detailed petrographic, geochemical (O-C-Sr isotopes) and fluid inclusion studies of the deeply buried Cambrian carbonates in the West-central Tarim Basin revealed three types of crystalline dolomites (fine-cry...
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Article
Open AccessEfficacy and Safety of Panobinostat in Relapsed or/and Refractory Multiple Myeloma: Meta Analyses of Clinical Trials and Systematic Review
During the past decades, many novel agents have improved response and survival of patients with multiple myeloma. Nevertheless, it remains challenging when they suffer relapsing. Thus, novel therapeutic agents...
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Article
Brain-derived neurotrophic factor induces proliferation, migration, and VEGF secretion in human multiple myeloma cells via activation of MEK-ERK and PI3K/AKT signaling
This study investigated the signaling pathways involved in the different biological effects of brain-derived neurotrophic factor (BDNF) in multiple myeloma (MM). The effects of BDNF on proliferation of MM cell...
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Article
Successful treatment of myeloid neoplasms associated with PDGFRA rearrangement with imatinib mesylate
Hypereosinophilic syndromes (HES) constitute a rare and heterogeneous group of disorders, defined as persistent and marked blood eosinophilia associated with evidence of eosinophil-induced organ damage. Cardia...
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Article
Resveratrol as a novel agent for treatment of multiple myeloma with matrix metalloproteinase inhibitory activity
To examine the in vitro antitumor activity of resveratrol against multiple myeloma (MM) cell lines (RPMI 8226, U266, and KM3), and the mechanisms involved.
