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  1. No Access

    Article

    New ursolic acid derivatives bearing 1,2,3-triazole moieties: design, synthesis and anti-inflammatory activity in vitro and in vivo

    In order to discover novel anti-inflammatory agents, three series of compounds obtained by appending 1,2,3-triazole moieties on ursolic acid were designed and synthesized. All compounds have been screened for ...

    Tian-Yi Zhang, Chun-Shi Li, Li-Ting Cao, Xue-Qian Bai, Dong-Hai Zhao… in Molecular Diversity (2022)

  2. No Access

    Article

    Synthesis and evaluation of ursolic acid-based 1,2,4-triazolo[1,5-a]pyrimidines derivatives as anti-inflammatory agents

    Here, two series of novel ursolic acid-based 1,2,4-triazolo[1,5-a]pyrimidines derivatives were synthesized and screened for their anti-inflammatory activity by evaluating their inhibition effect of using LPS-i...

    Tian-Yi Zhang, Chun-Shi Li, ** Li, Xue-Qian Bai, Shu-Ying Guo… in Molecular Diversity (2022)

  3. No Access

    Article

    Design, synthesis and evaluation of dihydrotriazine derivatives-bearing 5-aryloxypyrazole moieties as antibacterial agents

    In the present investigation, a series of dihydrotriazine derivatives-bearing 5-aryloxypyrazole moieties were synthesized and their structures were confirmed by different spectral tools. The biological evaluat...

    Tian-Yi Zhang, Chun-Shi Li, Ming-Yue Cui, Xue-Qian Bai… in Molecular Diversity (2021)

  4. No Access

    Article

    Synthesis and molecular docking studies of novel pyrimidine derivatives as potential antibacterial agents

    The present work describes the in vitro antibacterial evaluation of some new pyrimidine derivatives. Twenty-two target compounds were designed, synthesized and preliminarily explored for their antimicrobial ac...

    Xue-Qian Bai, Chun-Shi Li, Ming-Yue Cui, Ze-Wen Song, **ng-Yu Zhou… in Molecular Diversity (2020)