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Chapter
Myocardial Fibrosis: Structural Basis for Diastolic Dysfunction
Left ventricular hypertrophy (LVH) is the single most important prognostic factor associated with adverse cardiovascular events, including heart failure and sudden death, attributable to cardiovascular disease...
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Chapter
Gene Expression of Cardiac Myocytes: A Pharmacologic Target for the Failing Heart?
Despite recent advances in the management of congestive heart failure, the prognosis of patients with overloaded hypertrophied hearts remains poor [1]. Particular progress has been achieved in the treatment of...
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Article
Dietary linolenic acid-mediated increase in vascular prostacyclin formation
To define vascular effects of an enhanced dietary α-linolenic acid intake, 28 spontaneously hypertensive rats were fed a 3% sunflowerseed oil (44% linoleic acid) diet; in 3 groups (7 rats each), the diet was s...
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Article
Drug withdrawal and rebound hypertension: Differential action of the central antihypertensive drugs moxonidine and clonidine
To examine the antihypertensive action of the centrally acting antiadrenergic drugs moxonidine and clonidine, systolic and diastolic blood pressure as well as heart rate were monitored by radio telemetry in sp...
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Article
Aldosterone and Myocardial Fibrosis in Heart Failure