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Myocardial Fibrosis: Structural Basis for Diastolic Dysfunction

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Diastolic Relaxation of the Heart

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Abstract

Left ventricular hypertrophy (LVH) is the single most important prognostic factor associated with adverse cardiovascular events, including heart failure and sudden death, attributable to cardiovascular disease [1–4]. This is true for both the general population and patients with uncomplicated hypertension, irrespective of race, gender, or the presence of coronary artery disease. Echocardiographic left ventricular (LV) mass has been found to have prognostic value in excess of traditional risk factors, such as hypertension, diabetes, serum cholesterol, and obesity.

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Authors
  1. Karl T. Weber
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  2. Scott E. Campbell
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  3. Christian G. Brilla
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  4. Joseph S. Janicki
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Editors and Affiliations

  1. Harvard Medical School, USA

    Beverly H. Lorell M.D. (Associate Professor of Medicine, Director) & William Grossman M.D. (Dana Professor of Medicine, Chief) (Associate Professor of Medicine, Director) &  (Dana Professor of Medicine, Chief)

  2. Hemodynamic Research Laboratory, Beth Israel Hospital, Boston, Massachusetts, USA

    Beverly H. Lorell M.D. (Associate Professor of Medicine, Director) (Associate Professor of Medicine, Director)

  3. Cardiovascular Division, Beth Israel Hospital, Boston, Massachusetts, USA

    William Grossman M.D. (Dana Professor of Medicine, Chief) (Dana Professor of Medicine, Chief)

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Weber, K.T., Campbell, S.E., Brilla, C.G., Janicki, J.S. (1994). Myocardial Fibrosis: Structural Basis for Diastolic Dysfunction. In: Lorell, B.H., Grossman, W. (eds) Diastolic Relaxation of the Heart. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2594-3_22

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  • DOI: https://doi.org/10.1007/978-1-4615-2594-3_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6110-7

  • Online ISBN: 978-1-4615-2594-3

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