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Open AccessAnimal models to study the neurological manifestations of the post-COVID-19 condition
More than 40% of individuals infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have experienced persistent or relapsing multi-systemic symptoms months after the onset of coronavirus dise...
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Article
Open AccessSchlafen 12 restricts HIV-1 latency reversal by a codon-usage dependent post-transcriptional block in CD4+ T cells
Latency is a major barrier towards virus elimination in HIV-1-infected individuals. Yet, the mechanisms that contribute to the maintenance of HIV-1 latency are incompletely understood. Here we describe the Sch...
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Article
Open AccessVaccination with an HIV T-cell immunogen induces alterations in the mouse gut microbiota
The gut microbiota is emerging as a crucial factor modulating vaccine responses; however, few studies have investigated if vaccines, in turn, can alter the microbiota and to what extent such changes may improv...
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Article
Mechanisms involved in the Abacavir-mediated hypersensitivity syndrome
The potentially life-threatening adverse reactions to Abavacir (ABC), a nucleoside analog reverse transcriptase inhibitor for the treatment of HIV infection, have been known for several years to be limited to ...
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Article
HIV-1 over time: fitness loss or robustness gain?
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Article
Efficient generation of human T cells from a tissue-engineered thymic organoid
Biocompatible inorganic matrices have been used to enhance bone repair by integrating with endogenous bone architecture. Hypothesizing that a three-dimensional framework might support reconstruction of other t...