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Article
Open AccessThe burden of post-acute COVID-19 symptoms in a multinational network cohort analysis
Persistent symptoms following the acute phase of COVID-19 present a major burden to both the affected and the wider community. We conducted a cohort study including over 856,840 first COVID-19 cases, 72,422 re...
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Article
Open AccessAnimal models to study the neurological manifestations of the post-COVID-19 condition
More than 40% of individuals infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have experienced persistent or relapsing multi-systemic symptoms months after the onset of coronavirus dise...
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Article
Open AccessTime from symptoms onset to remdesivir is associated with the risk of ICU admission: a multicentric analyses
Shorter duration of symptoms before remdesivir has been associated with better outcomes. Our goal was to evaluate variables associated with the need of ICU admission in a cohort of hospitalized patients for CO...
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Article
Open AccessGlucocorticoids’ treatment impairs the medium-term immunogenic response to SARS-CoV-2 mRNA vaccines in Systemic Lupus Erythematosus patients
Limited data exists on SARS-CoV-2 sustained-response to vaccine in patients with rheumatic diseases. This study aims to evaluate neutralizing antibodies (nAB) induced by SARS-CoV-2 vaccine after 3 to 6 months ...
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Article
Open AccessInappropriate sinus tachycardia in post-COVID-19 syndrome
Inappropriate sinus tachycardia (IST) is a common observation in patients with post-COVID-19 syndrome (PCS) but has not yet been fully described to date. To investigate the prevalence and the mechanisms underl...
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Article
Open AccessSARS-CoV-2 infection elicits a rapid neutralizing antibody response that correlates with disease severity
The protective effect of neutralizing antibodies in SARS-CoV-2 infected individuals is not yet well defined. To address this issue, we have analyzed the kinetics of neutralizing antibody responses and their as...
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Article
Open AccessLegionella SBT applied directly to respiratory samples as a rapid molecular epidemiological tool
Legionnaires’ disease (LD) is an atypical pneumonia caused by the inhalation of Legionella. The methods used for the diagnosis of LD are direct culture of respiratory samples and urinary antigen detection. Howeve...
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Article
Differential Proteome Between Patient-Related and Non-related Environmental Isolates of Legionella pneumophila
Molecular epidemiologic studies of Legionella have shown different molecular types coexisting in the same environment, with only one having the ability to trigger an outbreak. We therefore studied the proteome of...
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Article
Comparative molecular and antibody ty** during the investigation of an outbreak of Legionnaires’ disease
An outbreak of Legionnaires’ disease with 113 confirmed cases was reported in the town of Mataró, Spain, in August 2002. In this study, we compared three different ty** methods and characterized the clinical...