6 Result(s)
within
Chi-Tan Hu
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessNovel urine cell-free DNA methylation markers for hepatocellular carcinoma
An optimized hepatocellular carcinoma (HCC)-targeted methylation next generation sequencing assay was developed to discover HCC-associated methylation markers directly from urine for HCC screening. Urine cell-...
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Article
Open AccessThioacetamide-induced liver damage and thrombocytopenia is associated with induction of antiplatelet autoantibody in mice
Thrombocytopenia is usually associated with liver injury, elevated plasma aspartate aminotransferase and alanine aminotransferase levels, and high antiplatelet immunoglobulin (Ig) titers, although the mechanis...
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Article
Open AccessAuthor Correction: Snail collaborates with EGR-1 and SP-1 to directly activate transcription of MMP 9 and ZEB1
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
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Article
Open AccessDevelopment and Evaluation of Novel Statistical Methods in Urine Biomarker-Based Hepatocellular Carcinoma Screening
Hepatocellular carcinoma is one of the fastest growing cancers in the US and has a low survival rate, partly due to difficulties in early detection. Because of HCC’s high heterogeneity, it has been suggested t...
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Article
Open AccessSnail collaborates with EGR-1 and SP-1 to directly activate transcription of MMP 9 and ZEB1
The Snail transcription factor plays as a master regulator of epithelial mesenchymal transition (EMT), one of the steps of tumor metastasis. Snail enhances expressions of a lot of mesenchymal genes including t...
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Article
Open AccessComprehensive DNA methylation analysis of hepatitis B virus genome in infected liver tissues
Hepatitis B virus (HBV) is a hepatotropic virus causing hepatitis, cirrhosis and hepatocellular carcinoma (HCC). The methylation status of the HBV DNA in its different forms can potentially provide insight int...
