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  1. Article

    Open Access

    Protein folding prediction in the HP model using ions motion optimization with a greedy algorithm

    The function of a protein is determined by its native protein structure. Among many protein prediction methods, the Hydrophobic-Polar (HP) model, an ab initio method, simplifies the protein folding prediction ...

    Cheng-Hong Yang, Kuo-Chuan Wu, Yu-Shiun Lin, Li-Yeh Chuang in BioData Mining (2018)

  2. Article

    Open Access

    Confronting two-pair primer design for enzyme-free SNP genoty** based on a genetic algorithm

    Polymerase chain reaction with confronting two-pair primers (PCR-CTPP) method produces allele-specific DNA bands of different lengths by adding four designed primers and it achieves the single nucleotide polym...

    Cheng-Hong Yang, Yu-Huei Cheng, Li-Yeh Chuang, Hsueh-Wei Chang in BMC Bioinformatics (2010)

  3. Article

    Open Access

    SNP-RFL** 2: an updated and integrated PCR-RFLP tool for SNP genoty**

    PCR-restriction fragment length polymorphism (RFLP) assay is a cost-effective method for SNP genoty** and mutation detection, but the manual mining for restriction enzyme sites is challenging and cumbersome....

    Hsueh-Wei Chang, Yu-Huei Cheng, Li-Yeh Chuang, Cheng-Hong Yang in BMC Bioinformatics (2010)

  4. Article

    Open Access

    V-MitoSNP: visualization of human mitochondrial SNPs

    Mitochondrial single nucleotide polymorphisms (mtSNPs) constitute important data when trying to shed some light on human diseases and cancers. Unfortunately, providing relevant mtSNP genoty** information in ...

    Li-Yeh Chuang, Cheng-Hong Yang, Yu-Huei Cheng, De-Leung Gu in BMC Bioinformatics (2006)