9 Result(s)
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Charles S. Greenberg
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Article
Impact of Benign Hematology Didactic Lectures on In-service Exam in a Hematology-Oncology Fellowship Program: a Cross-sectional Longitudinal Study
It remains unclear on whether the traditional formal didactic lecture sessions improve knowledge acquisition with conflicting data in the literature. This study evaluates the impact of an additional benign hem...
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Article
Analyzing the impact of systems-based hematologist in the healthcare system at an academic medical center
Over the next decade, there is a predicted shortage of nonmalignant hematologist to maintain the workforce in the United States. To address this, the American Society of Hematology described the creation of th...
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Article
Initial and long term impact of a multi-disciplinary task force in the diagnosis and management of heparin-induced thrombocytopenia
Many medical centers are faced with a major challenge in making an accurate diagnosis of heparin-induced thrombocytopenia (HIT) and ensuring appropriate changes in management strategy in line with guideline re...
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Article
Open AccessEndothelial cell-surface tissue transglutaminase inhibits neutrophil adhesion by binding and releasing nitric oxide
Nitric oxide (NO) produced by endothelial cells in response to cytokines displays anti-inflammatory activity by preventing the adherence, migration and activation of neutrophils. The molecular mechanism by whi...
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Article
Role of tissue transglutaminase-2 (TG2)-mediated aminylation in biological processes
Post-translational modification (PTM) is an important mechanism in modulating a protein’s structure and can lead to substantial diversity in biological function. Compared to other forms of PTMs such as phospho...
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Article
Histaminylation of fibrinogen by tissue transglutaminase-2 (TGM-2): potential role in modulating inflammation
Plasma fibrinogen plays an important role in hemostasis and inflammation. Fibrinogen is converted to fibrin to impede blood loss and serves as the provisional matrix that aids wound healing. Fibrinogen also bi...
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Chapter
Angiogenesis and Oxygen Transport in Solid Tumors
Angiogenesis, the formation of new vessels from existing microvasculature, is a tremendously complex and intricate process, essential for embryogenesis and development of multicellular organisms (1), but it occur...
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Article
Impermeant stilbene disulfonic acids block chemotactic peptide receptor function on human granulocytes
Anion transport is important in a variety of cell functions. 4,4′-Diisothiocyanostilbene-2,2′-disulfonic acid (DIDS) and 4-acetamido-4′-isothiocyanostilbene2,2′-disulfonic acid (SITS) are two impermeant agents...
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Article
Consequences of terbium (111) binding on the conformation and enzymatic activity of Guinea pig liver transglutaminase
Calcium ions are crucial for expression of transglutaminase activity. Although lanthanides have been reported to substitute for calcium in a variety of protein functions, they did not replace the calcium requi...
