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    Article

    The overexpression of MCPH1 inhibits cell growth through regulating cell cycle-related proteins and activating cytochrome c-caspase 3 signaling in cervical cancer

    MCPH1, initially identified as an hTERT repressor, has recently been implicated in mediating DNA damage response and maintaining chromosome integrity. This study is to investigate its potential role in the ons...

    Li Mai, Fa** Yi, **aoyan Gou, Ji Zhang in Molecular and Cellular Biochemistry (2014)

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    Article

    NFBD1/MDC1 is a protein of oncogenic potential in human cervical cancer

    A large nuclear protein of 2089 amino acids, NFBD1/MDC1 has recently been implicated in tumorigenesis and tumor growth. In this study, we investigated its expression in cervical cancers and explored its functi...

    Chengfu Yuan, Youquan Bu, Changdong Wang, Fa** Yi in Molecular and Cellular Biochemistry (2012)

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    Article

    Growth inhibition, morphology change, and cell cycle alterations in NFBD1-depleted human esophageal cancer cells

    NFBD1/MDC1 is a large nuclear protein mainly participating in DNA damage response, indicating its therapeutic potential as a radio-/chemosensitizer target in cancer field. Esophageal cancer ranks among one of ...

    Zhengmei Yang, Youquan Bu, Changdong Wang, Geli Liu in Molecular and Cellular Biochemistry (2010)