-
Article
Open AccessDivergent co-transcriptomes of different host cells infected with Toxoplasma gondii reveal cell type-specific host-parasite interactions
The apicomplexan parasite Toxoplasma gondii infects various cell types in avian and mammalian hosts including humans. Infection of immunocompetent hosts is mostly asymptomatic or benign, but leads to development ...
-
Chapter
Toxoplasma
Toxoplasma gondii is the most widespread intracellular parasite of warm-blooded vertebrates including humans. Infections are mostly asymptomatic or benign in immunocompetent hosts but can be life threatening in ...
-
Article
Open AccessApoptosis-like cell death pathways in the unicellular parasite Toxoplasma gondii following treatment with apoptosis inducers and chemotherapeutic agents: a proof-of-concept study
Ancient pathways of an apoptosis-like cell death have been identified in unicellular eukaryotes including protozoan parasites. Here, we examined programmed cell death in the apicomplexan Toxoplasma gondii which i...
-
Protocol
Introduction: Parasites
-
Protocol
Modulation of Caspase Activation by Toxoplasma gondii
Apoptosis plays crucial roles for the outcome of infection with various infectious agents. The host’s apoptotic program may be modulated after infection in order to combat the pathogen or to restrict the immun...
-
Article
Toxoplasma gondii glycosylphosphatidylinositols are not involved in T. gondii-induced host cell survival
Toxoplasma gondii is an intracellular parasite able to both promote and inhibit apoptosis. T. gondii renders infected cells resistant to programmed cell death induced by multiple apoptoti...
-
Article
Subversion of innate and adaptive immune responses by Toxoplasma Gondii
The intracellular apicomplexan parasite Toxoplasma gondii is able to survive and persist in immunocompetent intermediate hosts for the host’s life span. This is despite the induction of a vigorous humoral and—mor...
