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Open AccessCorrection to: Classical structural identifiability methodology applied to low-dimensional dynamic systems in receptor theory
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Open AccessClassical structural identifiability methodology applied to low-dimensional dynamic systems in receptor theory
Mathematical modelling has become a key tool in pharmacological analysis, towards understanding dynamics of cell signalling and quantifying ligand-receptor interactions. Ordinary differential equation (ODE) mo...
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Article
Open AccessLigand Binding Dynamics for Pre-dimerised G Protein-Coupled Receptor Homodimers: Linear Models and Analytical Solutions
Evidence suggests that many G protein-coupled receptors (GPCRs) are bound together forming dimers. The implications of dimerisation for cellular signalling outcomes, and ultimately drug discovery and therapeut...
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The Rights of State Hospital Patients: From State Hospitals to Their Alternatives
During the 1980s and 1990s the locus of psychiatric treatment in many states shifted from state hospitals to the psychiatric units of general hospitals. The extent to which the rights guaranteed to psychiatric...
