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Article

A versatile soluble siglec scaffold for sensitive and quantitative detection of glycan ligands

Sialic acid-binding immunoglobulin-type lectins (Siglecs) are immunomodulatory receptors that are regulated by their glycan ligands. The connections between Siglecs and human disease motivate improved methods ...

Emily Rodrigues, Jaesoo Jung, Hea** Park, Caleb Loo… in Nature Communications (2020)