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Article
Characterizing Sensory Phenotypes of Subgroups with a Known Genetic Etiology Pertaining to Diagnoses of Autism Spectrum Disorder and Intellectual Disability
We aimed to identify unique constellations of sensory phenotypes for genetic etiologies associated with diagnoses of autism spectrum disorder (ASD) and intellectual disability (ID). Caregivers reported on sens...
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Article
Social Connection Constellations and Individual Well-Being Typologies: Using the Loglinear Modeling Approach with Latent Variables
Despite a well-established association between social connection and well-being, it is unclear which aspects of social connection link to well-being in what ways. This gap in the literature necessitates a holi...
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Article
Feedback Related Negativity Amplitude is Greatest Following Deceptive Feedback in Autistic Adolescents
The purpose of this study is to investigate if feedback related negativity (FRN) can capture instantaneous elevated emotional reactivity in autistic adolescents. A measurement of elevated reactivity could allo...
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Article
Open AccessSocial attention to activities in children and adults with autism spectrum disorder: effects of context and age
Diminished visual monitoring of faces and activities of others is an early feature of autism spectrum disorder (ASD). It is uncertain whether deficits in activity monitoring, identified using a homogeneous set...
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Article
Open AccessClinical phenotype of ASD-associated DYRK1A haploinsufficiency
DYRK1A is a gene recurrently disrupted in 0.1–0.5% of the ASD population. A growing number of case reports with DYRK1A haploinsufficiency exhibit common phenotypic features including m...
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Article
Open AccessExploring the heterogeneity of neural social indices for genetically distinct etiologies of autism
Autism spectrum disorder (ASD) is a genetically and phenotypically heterogeneous disorder. Promising initiatives utilizing interdisciplinary characterization of ASD suggest phenotypic subtypes related to speci...
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Article
Open AccessModulation of mu attenuation to social stimuli in children and adults with 16p11.2 deletions and duplications
Copy number variations (CNV) within the recurrent ~600 kb chromosomal locus of 16p11.2 are associated with a wide range of neurodevelopmental disorders, including autism spectrum disorder (ASD). However, little i...
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Article
Brain Mechanisms for Processing Direct and Averted Gaze in Individuals with Autism
Prior studies have indicated brain abnormalities underlying social processing in autism, but no fMRI study has specifically addressed the differential processing of direct and averted gaze, a critical social c...
