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Chapter
Applications of Optical Resonance to Biological Sensing and Imaging: I. Spectral Self-Interference Microscopy
Fluorescence microscopy is an essential tool in modern biological research. It is a powerful method that allows noninvasive monitoring of specifically labeled targets within living cells, and simultaneous dete...
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Book
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Chapter and Conference Paper
Nomenclature Issues in the Human Genome Project
The recent progress in biotechnology, in particular in techniques to manipulate the genetic molecule DNA, has led to probably the most exciting, and also much debated enterprise in biology: to reveal the seque...
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Chapter and Conference Paper
The Packaging of DNA in Bacteriophage Lambda
The structure of bacteriophage lambda has been studied extensively by several groups using a variety of physical and chemical techniques. However, many aspects of bacteriophage structure remain unreasolved. It...
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Chapter
RNA Structure in Solution and on the 30S Ribosomal Subunit
Evidence continues to mount that RNA plays many vital structural and functional roles of the ribosome in protein synthesis (for a review see Thompson and Hearst, 1983 a). Indeed, the recent discovery of cataly...
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Article
Map** the structure of macromolecular assemblies by combining chemical modification and separation methods
Several examples will be described in which powerful separation methods are combined with relatively simple chemical modification techniques to provide structural information on complex macromolecular assembli...
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Chapter and Conference Paper
RNA Structure, Free and on the Ribosome, as Revealed by Chemical and Enzymatic Studies
At present, various chemical and enzymatic probes are the experimental techniques capable of providing large amounts of data on the structure and arrangement of large RNA molecules. Direct reactivity measureme...
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Book
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Article
Possible Conformations of 5S Ribosomal RNA
THE determination of the nucleotide sequence of two 5S ribosomal RNAs by Brownlee, Sanger and Barrell represents a major advance in our knowledge of the structure of ribonucleic acids1. This RNA contains only the...