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    Article

    Development of DNA delivery system using Pseudomonas exotoxin A and a DNA binding region of human DNA topoisomerase I

    Gene therapy is defined as the delivery of a functional gene for expression in somatic tissues with the intent to cure a disease. Thus, highly efficient gene transfer is essential for gene therapy. Receptor-m...

    T.-Y. Chen, C.-T. Hsu, K.-H. Chang, C.-Y. Ting in Applied Microbiology and Biotechnology (2000)

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    Article

    Recombinant protein composed of Pseudomonas exotoxin A, outer membrane proteins I and F as vaccine against P. aeruginosa infection

    We have constructed a chimeric protein composed of the receptor binding and membrane translocation domains of Pseudomonas exotoxin A (PE) with the outer membrane proteins I and F, together designated as PEIF. Th...

    T.-Y. Chen, H.-F. Shang, T.-L. Chen, C.-P. Lin in Applied Microbiology and Biotechnology (1999)

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    Article

    Genetic map** of DNA topoisomerase I-related sequences to mouse Chromosomes 2 and 14

    S. F. Kingsmore, C.-K. Lo, J. Hwang, C.-F. Hui, M. F. Seldin in Mammalian Genome (1994)

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    Chapter

    RNA Structure in Solution and on the 30S Ribosomal Subunit

    Evidence continues to mount that RNA plays many vital structural and functional roles of the ribosome in protein synthesis (for a review see Thompson and Hearst, 1983 a). Indeed, the recent discovery of cataly...

    C. R. Cantor, C.-F. Hui, C. Kang in Structure, Function, and Genetics of Ribos… (1986)

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    Article

    Map** the structure of macromolecular assemblies by combining chemical modification and separation methods

    Several examples will be described in which powerful separation methods are combined with relatively simple chemical modification techniques to provide structural information on complex macromolecular assembli...

    C. R. Cantor, R. Benezra, C-F. Hui, C. L. Smith, J. Welsh in Journal of Biosciences (1985)

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    Chapter and Conference Paper

    RNA Structure, Free and on the Ribosome, as Revealed by Chemical and Enzymatic Studies

    At present, various chemical and enzymatic probes are the experimental techniques capable of providing large amounts of data on the structure and arrangement of large RNA molecules. Direct reactivity measureme...

    P. L. Wollenzien, C. F. Hui, C. Kang, R. F. Murphy in Mechanisms of Protein Synthesis (1985)