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Article
Decreased global DNA methylation in the white blood cells of high fat diet fed vervet monkeys (Chlorocebus aethiops)
Epigenetic mechanisms are associated with the development of many chronic diseases and due to their reversible nature offer a unique window of opportunity to reverse the disease phenotype. This study investiga...
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Article
Evidence for repetitive load in the trapezius muscle during a tap** task
Many studies describe the trapezius muscle activation pattern during repetitive key-tap** focusing on continuous activation. The objectives of this study were to determine whether the upper trapezius is phas...
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Article
Kinetics of propiverine as assessed by radioreceptor assay in poor and extensive metabolizers of debrisoquine
A pharmacokinetic study with 30 mg propiverine p.o. was performed in healthy volunteers (10 males, 6 females, age 36–56 years, body weight 55–100 kg, body height 162–184 cm, Broca index 0.96–1.19). 8 of them w...
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Clinical Studies on Osteoporosis
Osteoporosis is, by definition, a reduction in bone mass with remaining bone of normal composition. The related loss in bone strength results in fractures with little or no abnormal force. Since a valid measur...