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  1. No Access

    Article

    Ecotropic viral integration site 1, a novel oncogene in prostate cancer

    Prostate cancer (PCa) is the most commonly diagnosed non-cutaneous cancer in men in the western world. Mutations in tumor suppressor genes and in oncogenes are important for PCa progression, whereas the role o...

    A Queisser, S Hagedorn, H Wang, T Schaefer, M Konantz, S Alavi, M Deng, W Vogel… in Oncogene (2017)

  2. No Access

    Article

    Lower dose anti-thymocyte globulin for GvHD prophylaxis results in improved survival after allogeneic stem cell transplantation

    In vivo T-cell depletion with anti-thymocyte globulin (ATG) can attenuate GvHD but may increase infection and relapse risks. ATG-Fresenius (ATG-F) at a dose of 60 mg/kg was standard GvHD prophylaxis in unrelated ...

    L Binkert, M Medinger, J P Halter, D Heim, S Gerull… in Bone Marrow Transplantation (2015)

  3. No Access

    Article

    Ruxolitinib in corticosteroid-refractory graft-versus-host disease after allogeneic stem cell transplantation: a multicenter survey

    Despite major improvements in allogeneic hematopoietic cell transplantation over the past decades, corticosteroid-refractory (SR) acute (a) and chronic (c) graft-versus-host disease (GVHD) cause high mortality...

    R Zeiser, A Burchert, C Lengerke, M Verbeek, K Maas-Bauer, S K Metzelder… in Leukemia (2015)

  4. No Access

    Article

    The regulatory interaction of EVI1 with the TCL1A oncogene impacts cell survival and clinical outcome in CLL

    Dysregulated T-cell leukemia/lymphoma-1A (TCL1A), a modulator in B-cell receptor (BCR) signaling, is causally implicated in chronic lymphocytic leukemia (CLL). However, the mechanisms of the perturbed TCL1A re...

    E Vasyutina, J M Boucas, J Bloehdorn, C Aszyk, G Crispatzu, M Stiefelhagen… in Leukemia (2015)

  5. No Access

    Article

    EVI-1 modulates leukemogenic potential and apoptosis sensitivity in human acute lymphoblastic leukemia

    The transcriptional regulator ecotropic viral integration site-1 (EVI-1) has mainly been studied for its role in myeloid malignancies, in which high EVI-1 levels are associated with particularly aggressive diseas...

    M Konantz, M C André, M Ebinger, M Grauer, H Wang, S Grzywna, O C Rothfuss… in Leukemia (2013)

  6. No Access

    Article

    Prospective comparison of PCR-based vs late mRNA-based preemptive antiviral therapy for HCMV infection in patients after allo-SCT

    Human CMV (HCMV)-directed preemptive therapy has helped to improve the outcome following allo-SCT. In this study, we evaluated the safety and efficacy of a late mRNA-based (NucliSens CMV pp67) anti-HCMV treatm...

    H Hebart, C Lengerke, P Ljungman, C V Paya, T Klingebiel… in Bone Marrow Transplantation (2011)

  7. No Access

    Article

    Evaluation of the COBAS Amplicor HCMV Monitor for early detection and monitoring of human cytomegalovirus infection after allogeneic stem cell transplantation

    Early diagnosis of human cytomegalovirus (HCMV) infection and the introduction of preemptive antiviral therapy have reduced HCMV-related mortality after allogeneic stem cell transplantation. A critical goal re...

    C Lengerke, T Ljubicic, C Meisner, J Loeffler, C Sinzger… in Bone Marrow Transplantation (2006)

  8. No Access

    Article

    Transient respiratory failure possibly associated to imatinib

    C. Lengerke, T. Brümmendorf, U. Herrlinger, M. Horger, L. Kanz… in Investigational New Drugs (2005)