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Article
Open AccessObservation of time-dependent internal charge amplification in a planar germanium detector at cryogenic temperature
For the first time, time-dependent internal charge amplification through impact ionization has been observed in a planar germanium (Ge) detector operated at cryogenic temperature. In a time period of 30 and 45...
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Article
Research on micro-deep drawing process of concial part with ultra-thin copper foil using multi-layered DLC film-coated die
During the miniaturization of specimen size, lubrication plays a very important role in microforming process. Size effect of friction occurs clearly when a kind of liquid lubricant is applied, and the ultra-th...
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Article
Dynamic Mode Decomposition of a Wing-Body Junction Flow
Junction flows are subject to an intense adverse pressure gradient and three-dimensional separation when encountering a wall-mounted obstacle. A dynamically rich horseshoe vortex system is formed in this regio...
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Article
Thermal oxidation behaviors and structures of Fe-9Cr-1Mo alloy
Isothermal oxidation behaviors of Fe-9Cr-1Mo alloy were investigated at 600, 700, 750 and 850 ∘C for 72 h in air atmosphere. The oxidation rates were measured using a thermogravimetric analyzer (TGA). The structu...
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Article
Correlation of preoperative ROMA scores with clinical stage in epithelial ovarian cancer patients
The significance of the Risk of Ovarian Malignancy Algorithm (ROMA) in differentiating benign and malignant ovarian lesions has been evidenced. In our clinical work, we found that advanced ovarian cancer were ...
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Article
INSR gene polymorphisms correlate with sensitivity to platinum-based chemotherapy and prognosis in patients with epithelial ovarian cancer
This study aimed to investigate the correlation between INSR gene polymorphisms on platinum-based chemotherapy sensitivity and prognosis in epithelial ovarian cancer (EOC). A total of 339 EOC patients receiving p...
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Article
Thermal reaction hazard research for isoprene
Isoprene is an important material used in the synthetic rubber industry, the applications have been extensively studied, but research into the safe use of this substance has been scanty. The lack of safety inf...
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Article
The relevance of Tim-3 polymorphisms and F protein to the outcomes of HCV infection
Hepatitis C virus (HCV) is one of the major causes of liver inflammation. The aim of this study was to investigate the associations of T-cell immunoglobulin and mucin domain-3 (Tim-3) polymorphisms and the alt...
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Article
Modeling of tool influence function for high-efficiency polishing
The M-shaped tool influence function (TIF) usually comes out when adopting a large tool offset at the high-efficiency polishing stage in bonnet polishing. Its modeling is as important as the Gaussian-like TIF ...
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Article
The combinational therapy of trastuzumab and cetuximab inhibits tumor growth in a patient-derived tumor xenograft model of gastric cancer
Gastric cancer (GC) is one of the leading causes of cancer mortality worldwide. Although therapeutic strategies for GC have improved, the prognosis for advanced GC remains poor. Herein, the present study sough...
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Article
Erratum: Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo
Correction to: Oncogene advance online publication 15 June 2015; doi:10.1038/onc.2015.215 Since the publication of the above article the authors have identified a number of errors in Supplemental Table S1: Che...
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Article
Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo
Signal transducer and activator of transcription 3 (STAT3) is constitutively activated in malignant tumors and has important roles in multiple aspects of cancer aggressiveness. Thus targeting STAT3 promises to...
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Article
Molecular changes after shockwave therapy in osteoarthritic knee in rats
This study investigated the molecular changes of DKK-1, MMP13, Wnt-5a and \(\upbeta \) ...
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Article
Differences in transport of photosynthates between high-and low-yielding Ipomoea batatas L. varieties
Previous studies have focused mainly on the accumulation of photosynthates and less on their distribution in sweet potato (Ipomoea batatas L.). In addition, the effect of photosynthate accumulation in root tubers...
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Article
TBX21 polymorphisms are associated with virus persistence in hepatitis C virus infection patients from a high-risk Chinese population
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and the varied outcomes of the infection depend on both viral and host factors. We have demonstrated that the HCV alternate reading f...
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Article
Open AccessSonic hedgehog through Gli2 and Gli3 is required for the proper development of placental labyrinth
Sonic hedgehog (Shh) functions as a conserved morphogen in the development of various organs in metazoans ranging from Drosophila to humans. Here, we have investigated the potential roles and underlying mechanism...
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Article
On the influence of low initial pressure and detonation stochastic nature on Mach reflection of gaseous detonation waves
The two-dimensional, time-dependent and reactive Navier–Stokes equations were solved to obtain an insight into Mach reflection of gaseous detonation in a stoichiometric hydrogen-oxygen mixture diluted by 25 % ...
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Article
Effects of self-correlation time on stability of metastable state in logistic model
Effects of colored noise on stability of metastable state in logistic model are studied by means of Fox approach and steepest-descent approximation. The expression for mean first-passage time from metastable s...
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Article
Efficacy of home-based virtual cycling training on bone mineral density in ambulatory children with cerebral palsy
The 12-week home-based virtual cycling training (hVCT) improved lower limb muscle strength and areal bone mineral density (aBMD) than the control program in children with cerebral palsy (CP). A muscle strength...
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Article
Hydrothermal synthesis, crystal structural, and thermal properties of a 1D zinc coordination polymer based on benzoate and flexible bis(benzimidazole) ligands
A new coordination polymer, [Zn(PhCOO)2(Bbbm)] n (I), where Bbbm = 1,1′-(1,4-butanediyl)bis-1H-benzimidazole, has been synthesized under hydrothermal conditions and characterize...
