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  1. Article

    Open Access

    Genetic determinants of micronucleus formation in vivo

    Genomic instability arising from defective responses to DNA damage1 or mitotic chromosomal imbalances2 can lead to the sequestration of DNA in aberrant extranuclear structures called micronuclei (MN). Although MN...

    D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros… in Nature (2024)

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  2. Article

    Open Access

    The role of sex and body weight on the metabolic effects of high-fat diet in C57BL/6N mice

    Metabolic disorders are commonly investigated using knockout and transgenic mouse models on the C57BL/6N genetic background due to its genetic susceptibility to the deleterious metabolic effects of high-fat di...

    C Ingvorsen, N A Karp, C J Lelliott in Nutrition & Diabetes (2017)

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  3. Article

    Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1β involves reductions in long-chain acyl-CoA levels and oxidative stress

    To determine if acute overexpression of peroxisome proliferator-activated receptor, gamma, coactivator 1 beta (Pgc-1β [also known as Ppargc1b]) in skeletal muscle improves insulin action in a rodent model of diet...

    L. E. Wright, A. E. Brandon, A. J. Hoy, G.-B. Forsberg, C. J. Lelliott… in Diabetologia (2011)

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