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Article
Open AccessMitochondrial complex I activity in microglia sustains neuroinflammation
Sustained smouldering, or low-grade activation, of myeloid cells is a common hallmark of several chronic neurological diseases, including multiple sclerosis1. Distinct metabolic and mitochondrial features guide t...
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Article
Open AccessGenetic determinants of micronucleus formation in vivo
Genomic instability arising from defective responses to DNA damage1 or mitotic chromosomal imbalances2 can lead to the sequestration of DNA in aberrant extranuclear structures called micronuclei (MN). Although MN...
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Chapter and Conference Paper
TEM investigations of aluminum precipitate in eutectic Si of A356 based alloys
Solidification of hypoeutectic type A356 alloys start with growth of primary aluminum (α-phase), followed by Al-Si eutectic [1]. Precipitation of Si, together with other added elements from aluminum has been e...
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Chapter and Conference Paper
Modelling of Fatigue Damage in Aluminum Cylinder Heads
Because of the regular increase in specific power, automotive cylinder heads, in particular those used in Diesel direct injection engines, are exposed to increasing thermomechanical loadings. Those cylinder he...