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Article
Early locoregional high-dose radiotherapy is associated with long-term disease control in localized primary angiocentric lymphoma of the nose and nasopharynx
Nasal NK/T cell is a rare form of usually localized non-Hodgkin's lymphoma (NHL) which generally carries a poor prognosis when treated with conventional NHL chemotherapy protocols. We reviewed 20 consecutive l...
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Article
Open AccessRandomized trial of neoadjuvant chemotherapy in oropharyngeal carcinoma
The objective of the study was to evaluate the effect of neoadjuvant chemotherapy on the survival of patients with oropharyngeal cancer. Patients with a squamous cell carcinoma of the oropharynx for whom curat...
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Article
Open AccessA phase II study of docetaxel in patients with metastatic squamous cell carcinoma of the head and neck
This study was designed to evaluate the activity, safety and tolerance of docetaxel (D) in a selected population with metastatic squamous cell carcinoma of the head and neck (SCCHN). Twenty-four patients with ...
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Article
Effective treatment of cutaneous and subcutaneous malignant tumours by electrochemotherapy
Electrochemotherapy (ECT) enhances the effectiveness of chemotherapeutic agents by administering the drug in combination with short intense electric pulses. ECT is effective because electric pulses permeabiliz...
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Chapter and Conference Paper
Treatment of Oropharynx Carcinomas: Experience at the Institut Gustave-Roussy
Radiotheraphy (RT) alone is he preffered treatment of oropharynx carcinomas T1, T2, N0 and N1 at te Institut Gustave-Roussy (IGR). More advanced or ulcerative tumours are treated with surgery combined with RT....
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Chapter and Conference Paper
Phase I-II trial of Seraspenide (AcSDKP): a supressor of myelopoiesis protects against chemotherapy myelotoxicity (version 10 february 1993)
The Colony Forming Units in the Spleen (CFU-S), pluripotent stem cells in mice, are normally quiescent and it has been demonstrated that they are therefore relatively protected from the toxicity of drugs until...
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Chapter and Conference Paper
Perioperative chemotherapy in hypopharyngeal squamous cell carcinomas (SCC)
This study was designed to reduce the rate of distant metastasis and lessen the rate of locoregional recurrences of hypopharyngeal SCC by adding to the initial chemotherapy a post-operative chemotherapy, befor...
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Article
Phase II study of mitozolomide (M & B 39,565) in head and neck cancer
Nineteen patients with advanced head and neck cancer were given mitozolomide (MTZ), i.v. infusion, every 6 weeks. The starting dose was 100 mg m−2. When it was well tolerated, dose escalation was performed up to ...
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Chapter
Post-Radiotherapy Adjuvant Chemotherapy of Regionally Advanced UNPC: Increase in Disease Free Survival
38 patients with NPC, most of them from North Africa and South of Italy, with histo and serological diagnosis of UNPC (undifferentiated nasopharyngeal carcinoma), seen from January ‘83 till December ’84 at the In...