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    Article

    Early locoregional high-dose radiotherapy is associated with long-term disease control in localized primary angiocentric lymphoma of the nose and nasopharynx

    Nasal NK/T cell is a rare form of usually localized non-Hodgkin's lymphoma (NHL) which generally carries a poor prognosis when treated with conventional NHL chemotherapy protocols. We reviewed 20 consecutive l...

    V Ribrag, MEll Hajj, F Janot, T Girinsky, C Domenge, G Schwaab, P Fenaux in Leukemia (2001)

  2. Article

    Open Access

    Randomized trial of neoadjuvant chemotherapy in oropharyngeal carcinoma

    The objective of the study was to evaluate the effect of neoadjuvant chemotherapy on the survival of patients with oropharyngeal cancer. Patients with a squamous cell carcinoma of the oropharynx for whom curat...

    C Domenge, C Hill, J L Lefebvre, D De Raucourt, B Rhein in British Journal of Cancer (2000)

  3. Article

    Open Access

    A phase II study of docetaxel in patients with metastatic squamous cell carcinoma of the head and neck

    This study was designed to evaluate the activity, safety and tolerance of docetaxel (D) in a selected population with metastatic squamous cell carcinoma of the head and neck (SCCHN). Twenty-four patients with ...

    C Couteau, N Chouaki, S Leyvraz, D Oulid-Aissa, A Lebecq in British Journal of Cancer (1999)

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    Article

    Effective treatment of cutaneous and subcutaneous malignant tumours by electrochemotherapy

    Electrochemotherapy (ECT) enhances the effectiveness of chemotherapeutic agents by administering the drug in combination with short intense electric pulses. ECT is effective because electric pulses permeabiliz...

    LM Mir, LF Glass, G Serša, J Teissié, C Domenge, D Miklavčič in British Journal of Cancer (1998)

  5. No Access

    Chapter and Conference Paper

    Treatment of Oropharynx Carcinomas: Experience at the Institut Gustave-Roussy

    Radiotheraphy (RT) alone is he preffered treatment of oropharynx carcinomas T1, T2, N0 and N1 at te Institut Gustave-Roussy (IGR). More advanced or ulcerative tumours are treated with surgery combined with RT....

    F. Eschwège, P. Wibault, A. Lusinchi in Carcinoma of the Oral Cavity and Oropharynx (1994)

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    Chapter and Conference Paper

    Phase I-II trial of Seraspenide (AcSDKP): a supressor of myelopoiesis protects against chemotherapy myelotoxicity (version 10 february 1993)

    The Colony Forming Units in the Spleen (CFU-S), pluripotent stem cells in mice, are normally quiescent and it has been demonstrated that they are therefore relatively protected from the toxicity of drugs until...

    P. Carde, E. Gonçalves, F. Isnard, E. Deschamps de Paillette in Cancer Treatment An Update (1994)

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    Chapter and Conference Paper

    Perioperative chemotherapy in hypopharyngeal squamous cell carcinomas (SCC)

    This study was designed to reduce the rate of distant metastasis and lessen the rate of locoregional recurrences of hypopharyngeal SCC by adding to the initial chemotherapy a post-operative chemotherapy, befor...

    G. Mamelle, C. Domenge, F. Eschwege in Proceedings of the 3rd International Congr… (1991)

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    Article

    Phase II study of mitozolomide (M & B 39,565) in head and neck cancer

    Nineteen patients with advanced head and neck cancer were given mitozolomide (MTZ), i.v. infusion, every 6 weeks. The starting dose was 100 mg m−2. When it was well tolerated, dose escalation was performed up to ...

    P. Herait, J. P. Armand, M. Benahmed in Medical Oncology and Tumor Pharmacotherapy (1989)

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    Chapter

    Post-Radiotherapy Adjuvant Chemotherapy of Regionally Advanced UNPC: Increase in Disease Free Survival

    38 patients with NPC, most of them from North Africa and South of Italy, with histo and serological diagnosis of UNPC (undifferentiated nasopharyngeal carcinoma), seen from January ‘83 till December ’84 at the In...

    C. Domenge, J. L. Marin, J. P. Droz, F. Eschwege in Epstein-Barr Virus and Human Disease (1987)