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Article
Superior rectal artery preservation to reduce anastomotic leak rates in familial adenomatous polyposis patients treated with total colectomy and ileorectal anastomosis
Total colectomy with ileorectal anastomosis (TC/IRA) is one of the prophylactic surgical options in patients with familial adenomatous polyposis (FAP). This study investigated the effectiveness of superior rec...
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Article
Factors affecting recurrence in Crohn's disease Results of a prospective audit
It has been suggested that certain clinical and morphological features can modify the outcome of Crohn's disease, particularly regarding recurrence after surgery. A series of 233 patiens was followed prospect...
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Article
Microbiology
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Article
Interleukin 1β (IL-1β) release from fresh and cultured colonic mucosa in patients with ulcerative colitis (UC)
Interleukin-1, a cytokine produced by macrophages and other tissue cells, has a major role in inflammatory and immunological responses. Increased levels of IL-1 activity have been reported in experimental coli...
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Article
Influence of steroid treatment's duration in patients with active Crohn's disease
Steroids are very useful drugs in the treatment of active Crohn's disease (CD), but clinical relapses after steroid withdrawal may be very high.
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Article
Influence of steroid treatment's duration in patients with active Crohn's disease
Steroids are very useful drugs in the treatment of active Crohn's disease (CD), but clinical relapses after steroid withdrawal may be very high.
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Article
Interleukin 1β (IL-1β) release from fresh and cultured colonic mucosa in patients with ulcerative colitis (UC)
Interleukin-1, a cytokine produced by macrophages and other tissue cells, has a major role in inflammatory and immunological responses. Increased levels of IL-1 activity have been reported in experimental coli...
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Article
Topical treatment with 5-aminosalicylic in distal ulcerative colitis by using a new suppository preparation
Sixty-two patients with ulcerative colitis localised to the distal sigmoid colon and rectum (<20 cm) entered the trial. Thirty-two were treated with 5-ASA 500 mg suppositories (Asacol) 3 times a day for 1 mont...
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Article
Reduction by cimetropium bromide of the colonic motor response to eating in patients with the irritable bowel syndrome
Cimetropium bromide is an antimuscarinic compound with antispasmodic properties. Its effect on meal-stimulated sigmoid motor activity in 30 patients with the irritable bowel syndrome, mainly with pain and cons...
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Article
Efficacy of 5-aminosalicylic acid enemas versus hydrocortisone enemas in ulcerative colitis
A controlled trial has been carried out in order to compare the efficacy of enemas containing a high dosage of 5-ASA (4g) versus enemas containing hydrocortisone 100 mg. The trial was conducted on 86 patients,...
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Article
Effect of domperidone and dopamine on colonic motor activity in patients with the irritable bowel syndrome
The effect of domperidone, a peripheral antidopaminergic drug, on sigmoid motor activity in the irritable bowel syndrome, has been evaluated by measuring pressures in 3 opentipped tubes perfused with distilled...
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Chapter
Intestinal Transit time is Related with Different Anorectal Motility Patterns in Chronic Non-Organic Constipation
Constipation is a symptom common to many and different dis eases. It is due, at any rate, to an altered transit of intestinal contents, but it can be a secondary symptom in an organic intestinal and extraintes...
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Article
Inhibition of postprandial colonic motility by sulpiride in patients with irritable colon
Sulpiride, a benzamide derivative, selectively antagonizes dopaminergic receptors within and outside the central nervous system. Dopamine has previously been shown to increase colonic motility. In the present ...