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  1. Article

    E2F1 controls alternative splicing pattern of genes involved in apoptosis through upregulation of the splicing factor SC35

    The transcription factor E2F1 has a key function during S phase progression and apoptosis. It has been well-demonstrated that the apoptotic function of E2F1 involves its ability to transactivate pro-apoptotic ...

    G Merdzhanova, V Edmond, S De Seranno, A Van den Broeck… in Cell Death & Differentiation (2008)

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  2. Article

    E2F1 induces apoptosis and sensitizes human lung adenocarcinoma cells to death-receptor-mediated apoptosis through specific downregulation of c-FLIPshort

    E2F1 is a transcription factor that plays a well-documented role during S phase progression and apoptosis. We had previously postulated that the low level of E2F1 in primary lung adenocarcinoma contributes to ...

    C Salon, B Eymin, O Micheau, L Chaperot, J Plumas… in Cell Death & Differentiation (2006)

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    Oligomer-mediated modulation of hTERT alternative splicing induces telomerase inhibition and cell growth decline in human prostate cancer cells

    The expression of telomerase in human cells is strictly controlled by multiple mechanisms including transcription and alternative splicing of telomerase reverse transcriptase (hTERT). In this study, we demons...

    C. Brambilla, M. Folini, P. Gandellini… in Cellular and Molecular Life Sciences CMLS (2004)