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  1. Article

    miR-205 regulates basement membrane deposition in human prostate: implications for cancer development

    The basement membrane (BM) is a layer of specialized extracellular matrix that surrounds normal prostate glands and preserves tissue integrity. Lack or discontinuity of the BM is a prerequisite for tumor cell ...

    P Gandellini, V Profumo, A Casamichele, N Fenderico… in Cell Death & Differentiation (2012)

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  2. Article

    Open Access

    Apollon gene silencing induces apoptosis in breast cancer cells through p53 stabilisation and caspase-3 activation

    We analysed the effects of small interfering RNA (siRNA)-mediated silencing of Apollon, a member of the inhibitors of apoptosis protein family, on the proliferative potential and ability of human breast cancer...

    A Lopergolo, M Pennati, P Gandellini, N I Orlotti, P Poma… in British Journal of Cancer (2009)

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  3. No Access

    Article

    Oligomer-mediated modulation of hTERT alternative splicing induces telomerase inhibition and cell growth decline in human prostate cancer cells

    The expression of telomerase in human cells is strictly controlled by multiple mechanisms including transcription and alternative splicing of telomerase reverse transcriptase (hTERT). In this study, we demons...

    C. Brambilla, M. Folini, P. Gandellini… in Cellular and Molecular Life Sciences CMLS (2004)