-
Chapter and Conference Paper
Patterns of Relapse Following Focal Irradiation of Intracranial Germinoma: Critical Review of TGM-TC90 SFOP protocol
In the SFOP protocol TGM-TC90 for localised tumours, craniospinal (CS) prophylactic radiotherapy fields were replaced by carboplatin-based chemotherapy together with focal irradiation of the initial tumour vol...
-
Chapter and Conference Paper
Treatment of Primary Intracranial Germ Cell Tumours with Carboplatin-based Chemotherapy and Focal Irradiation
In the SFOP TC-90 and TC-92 protocols, patients with intracranial germinomas and secreting germ cell tumours (sGCT) were treated with a combination of chemotherapy and focal radiotherapy. One chemotherapy cycl...
-
Chapter and Conference Paper
Intracranial Malignant Germ Cell Tumours (CNS GCTs): Interim Results of the SIOP Trial
A European protocol for malignant CNS GCTs was initiated in 1996. The purpose was to compare patients with germinoma treated either with reduced craniospinal irradiation (CSI) (24 Gy craniospinal/16 Gy tumour ...
-
Chapter and Conference Paper
Treatment Strategy for Childhood Extracranial Secreting Germ Cell Tumours Based on Alphafoetoprotein (AFP) Level: Protocol TGM95 of the Société Française d’Oncologie Pédiatrique (SFOP)
The previous SFOP TGM85 and TGM90 studies showed that carboplatin (400 mg/m2) was less efficient that cisplatin (100 mg/m2), that patients with AFP levels over 15000 ng/ml had a worse outcome, and that the VIP re...