32 Result(s)

Article

Assessment of Karnofsky (KPS) and WHO (WHO-PS) performance scores in brain tumour patients: the role of clinician bias

Inclusion of brain tumour patients in oncological protocols may be hampered by their neurological impairment. The goal of this study was to assess the reliability of Karnofsky Performance Scale (KPS) and WHO P...

D. Frappaz, A. Bonneville-Levard, D. Ricard, S. Carrie… in Supportive Care in Cancer (2021)

Article

Pre-radiation chemotherapy improves survival in pediatric diffuse intrinsic pontine gliomas

The median survival of patients with diffuse intrinsic pontine glioma (DIPG) remains less than 1 year. The BSG 98 pre-irradiation chemotherapy protocol showed a significant increase in overall survival. In con...

Z. Gokce-Samar, P. A. Beuriat, C. Faure-Conter, C. Carrie… in Child's Nervous System (2016)

Article

Human chorionic gonadotropin elevation is not an intracranial germ cell tumor signature

P. Bourdillon, D. Frappaz, A. Vasiljevic, E. Jouanneau in Acta Neurochirurgica (2013)

Article

Role of surgery, radiotherapy and chemotherapy in papillary tumors of the pineal region: a multicenter study

Papillary tumor of the pineal region (PTPR), recently described as a distinct clinicopathological entity, can show aggressive biological behavior. The optimal therapeutic approach of PTPR has not been well def...

F. Fauchon, M. Hasselblatt, A. Jouvet, J. Champier, M. Popovic… in Journal of Neuro-Oncology (2013)

Article

Clear cell ependymoma with trisomy 19 develo** bone metastases

M. Payet, C. Conter, F. Labrousse, A. Maues De Paula… in Child's Nervous System (2012)

Chapter

Système nerveux central

Les tumeurs germinales malignes (TGM) intracrâniennes sont rares. Leur histologie est similaire à celle des TGM extracrâniennes. Elles concernent principalement l’adolescent et leur pronostic est...

M.-P. Sunyach, C. Conter, D. Frappaz in Tumeurs malignes rares (2010)

Article

Prise en charge des tumeurs cérébrales pédiatriques

La prise en charge des tumeurs cérébrales pédiatriques vise à améliorer les taux de survie, sans accepter des séquelles incompatibles avec une bonne qualité ultérieure de vie. Le modèle du médulloblastome est ...

D. Frappaz, A. Szathmari, S. Gonzalez, A. Pagnier in Oncologie (2006)

Article

High and Low Grade Oligodendrogliomas (ODG): Correlation of Amino-Acid and Glucose Uptakes Using PET and Histological Classifications

Classification and treatment strategy of Oligodendrogliomas (ODG) remain controversial. Imaging relies essentially on contrast enhancement using CT or MRI. The aim of our study was to use positron emission tom...

F. Giammarile, L.E. Cinotti, A. Jouvet, J.M. Ramackers… in Journal of Neuro-Oncology (2004)

Article

Intracranial Ependymomas in Adult Patients: Analyses of Prognostic Factors

Objective: The goal of our study is to identify significant prognostic factors for a series of intracranial ependymomas in an adult population. Age, location, histology, preoperative clinical status, extent of r...

J. Guyotat, F. Signorelli, S. Desme, D. Frappaz, G. Madarassy… in Journal of Neuro-Oncology (2002)

Chapter and Conference Paper

Patterns of Relapse Following Focal Irradiation of Intracranial Germinoma: Critical Review of TGM-TC90 SFOP protocol

In the SFOP protocol TGM-TC90 for localised tumours, craniospinal (CS) prophylactic radiotherapy fields were replaced by carboplatin-based chemotherapy together with focal irradiation of the initial tumour vol...

C. Alapetite, C. Carrie, H. Brisse, P. Thiesse, J-L. Habrand… in Germ Cell Tumours V (2002)

Chapter and Conference Paper

Treatment of Primary Intracranial Germ Cell Tumours with Carboplatin-based Chemotherapy and Focal Irradiation

In the SFOP TC-90 and TC-92 protocols, patients with intracranial germinomas and secreting germ cell tumours (sGCT) were treated with a combination of chemotherapy and focal radiotherapy. One chemotherapy cycl...

C. Patte, D. Frappaz, M. A. Raquin, E. Bouffet, C. Kalifa… in Germ Cell Tumours V (2002)

Chapter and Conference Paper

Intracranial Malignant Germ Cell Tumours (CNS GCTs): Interim Results of the SIOP Trial

A European protocol for malignant CNS GCTs was initiated in 1996. The purpose was to compare patients with germinoma treated either with reduced craniospinal irradiation (CSI) (24 Gy craniospinal/16 Gy tumour ...

G. Calaminus, M. L. Garré, J. R. Mann, C. Patte, R. Kortmann… in Germ Cell Tumours V (2002)

Chapter and Conference Paper

Impact of Residual Lesions in Intracranial Germinoma — Interim Results from the SIOP CNS GCT 96 Study

The significance of residual lesions after therapy for intracranial germinomas remains a controversial issue [1]. We therefore assessed: a) the frequency of residual tumour after surgery, b) the frequency of r...

S. Eisert, J. Nicholson, F. Saran, M. L. Garré, D. Frappaz, U. Göbel… in Germ Cell Tumours V (2002)

Chapter and Conference Paper

Treatment Strategy for Childhood Extracranial Secreting Germ Cell Tumours Based on Alphafoetoprotein (AFP) Level: Protocol TGM95 of the Société Française d’Oncologie Pédiatrique (SFOP)

The previous SFOP TGM85 and TGM90 studies showed that carboplatin (400 mg/m²) was less efficient that cisplatin (100 mg/m²), that patients with AFP levels over 15000 ng/ml had a worse outcome, and that the VIP re...

C. Patte, E. Quintana, D. Frappaz, P. Lutz, G. Leverger, C. Behar… in Germ Cell Tumours V (2002)

Article

Intracystic chemotherapy with bleomycin in the treatment of craniopharyngiomas

Object: Since bleomycin has not yet been used very frequently in the treatment of patients with craniopharyngioma, it seemed important to document the course of a series of such patients treated...

C. Mottolese, H. Stan, M. Hermier, P. Berlier, J. Convert… in Child's Nervous System (2001)

Article

Metastasis of Clear-Cell Renal Carcinoma to Cerebellar Hemangioblastoma in von Hippel Lindau Disease: Rare or not Investigated?

C. Mottolese, H. Stan, F. Giordano, D. Frappaz, D. Alexei… in Acta Neurochirurgica (2001)