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  1. No Access

    Article

    Association between COMT (Val158Met) functional polymorphism and early onset in patients with major depressive disorder in a European multicenter genetic association study

    The available data from preclinical and pharmacological studies on the role of the C-O-methyl transferase (COMT) support the hypothesis that abnormal catecholamine transmission has been implicated in the patho...

    I Massat, D Souery, J Del-Favero, M Nothen, D Blackwood, W Muir… in Molecular Psychiatry (2005)

  2. No Access

    Article

    Further evidence for a possible association between serotonin transporter gene and lithium prophylaxis in mood disorders

    We previously reported an association between the functional polymorphism in the upstream regulatory region of the serotonin transporter gene (SERTPR) and the prophylactic efficacy of lithium in a sample of 20...

    A Serretti, P N Malitas, L Mandelli, C Lorenzi, C Ploia… in The Pharmacogenomics Journal (2004)

  3. Article

    Open Access

    Neuropsychological outcome in children with optic pathway tumours when first-line treatment is chemotherapy

    Standard treatment of optic pathways gliomas consists of radiotherapy and surgery when feasible. Owing to the toxicity of irradiation, chemotherapy has emerged as an interesting therapeutic option, especially ...

    E Lacaze, V Kieffer, A Streri, C Lorenzi, E Gentaz… in British Journal of Cancer (2003)

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  4. No Access

    Article

    No occurrence of the glutamate transporter EAAT2 A206G polymorphism in schizophrenic subjects

    M Catalano, C Lorenzi, L Bocchio, G Racagni in Molecular Psychiatry (2002)

  5. No Access

    Article

    Serotonin transporter gene (5-HTTLPR) and major psychoses

    Serotoninergic neurotransmitter systems have been implicated in the pathogenesis of major psychoses. A functional polymorphism (5-HTTLPR) in the upstream regulatory region of the gene (SLC6A4) has been associa...

    A Serretti, R Lilli, C Lorenzi, E Lattuada, C Cusin, E Smeraldi in Molecular Psychiatry (2002)

  6. No Access

    Article

    Serotonin transporter gene associated with lithium prophylaxis in mood disorders

    The aim of this study was to investigate the possible association between the functional polymorphism in the upstream regulatory region of the serotonin transporter gene (5-HTTLPR) and the prophylactic efficac...

    A Serretti, R Lilli, L Mandelli, C Lorenzi, E Smeraldi in The Pharmacogenomics Journal (2001)

  7. No Access

    Article

    Dopamine receptor D2 Ser/Cys 311 variant is associated with delusion and disorganization symptomatology in major psychoses

    The D2 receptor (DRD2) is a binding site of many psychoactive drugs and it has been proposed as a genetic risk factor for psychiatric disorders. The aim of this investigation was to study the DRD2 S311C varian...

    A Serretti, E Lattuada, C Lorenzi, R Lilli, E Smeraldi in Molecular Psychiatry (2000)