Skip to main content

7 Result(s)

within Bryan G. Allen Remove this filter

and

  1. No Access

    Chapter

    Targeting Tumor Metabolism to Overcome Radioresistance

    Metabolic reprogramming is a hallmark of cancer. Altered metabolism provides a survival advantage for cancer cells during tumorigenesis by supplying resources needed for uncontrolled growth and increased rates...

    Daniel Wahl, Michael Petronek, Rashmi Ramachandran… in Molecular Targeted Radiosensitizers (2020)

  2. Article

    Open Access

    Deep segmentation networks predict survival of non-small cell lung cancer

    Non-small-cell lung cancer (NSCLC) represents approximately 80–85% of lung cancer diagnoses and is the leading cause of cancer-related death worldwide. Recent studies indicate that image-based radiomics featur...

    Stephen Baek, Yusen He, Bryan G. Allen, John M. Buatti… in Scientific Reports (2019)

    Download PDF (2059 KB) View Article

  3. No Access

    Chapter

    Metabolic Production of H2O2 in Carcinogenesis and Cancer Treatment

    The metabolic production of O2 •− and H2O2 in the presence of redox active metal ions is known to contribute to several steps involved with initiation, promotion, and progression of carcinogenesis that can induce...

    Bryan G. Allen, Douglas R. Spitz in Redox-Active Therapeutics (2016)

  4. No Access

    Protocol

    Using ΦC31 Integrase to Mediate Insertion of DNA in Xenopus Embryos

    The two most common methods used to generate transgenic Xenopus embryos, restriction enzyme-mediated insertion, and I-SceI meganuclease take advantage of relatively common but spatially unpredictable double-stran...

    You E. Li, Bryan G. Allen, Daniel L. Weeks in Xenopus Protocols (2012)

  5. No Access

    Protocol

    Bacteriophage φC31 Integrase Mediated Transgenesis in Xenopus laevis for Protein Expression at Endogenous Levels

    Bacteriophage φC31 inserts its genome into that of its host bacterium via the integrase enzyme which catalyzes recombination between a phage attachment site (attP) and a bacterial attachment site (attB). Integras...

    Bryan G. Allen, Daniel L. Weeks in Microinjection (2009)

  6. No Access

    Article

    Using phiC31 integrase to make transgenic Xenopus laevis embryos

    Bacteriophage phiC31 produces the enzyme integrase that allows the insertion of the phage genome into its bacterial host. This enzyme recognizes a specific DNA sequence in the phage (attP) and a different sequenc...

    Bryan G Allen, Daniel L Weeks in Nature Protocols (2006)

  7. No Access

    Article

    Transgenic Xenopus laevis embryos can be generated using φC31 integrase

    Bacteriophage φC31 encodes an integrase that can mediate the insertion of extrachromosomal DNA into genomic DNA. Here we show that the coinjection of mRNA encoding φC31 integrase with plasmid DNA encoding the ...

    Bryan G Allen, Daniel L Weeks in Nature Methods (2005)