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Article
Open AccessMacroalgal microbiomes unveil a valuable genetic resource for halogen metabolism
Macroalgae, especially reds (Rhodophyta Division) and browns (Phaeophyta Division), are known for producing various halogenated compounds. Yet, the reasons underlying their production and the fate of these met...
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Article
Open AccessInter-comparison of marine microbiome sampling protocols
Research on marine microbial communities is growing, but studies are hard to compare because of variation in seawater sampling protocols. To help researchers in the inter-comparison of studies that use differe...
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Article
Open AccessNatural and after colon washing fecal samples: the two sides of the coin for investigating the human gut microbiome
To date several studies address the important role of gut microbiome and its interplay with the human host in the health and disease status. However, the selection of a universal sampling matrix representative...
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Article
Morphological, molecular, and biochemical study of cyanobacteria from a eutrophic Algerian reservoir (Cheffia)
The cyanobacteria management in water bodies requires a deep knowledge of the community composition. Considering the reliable and thorough information provided by the polyphasic approach in cyanobacteria taxon...
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Article
Open AccessMicrobiome composition indicate dysbiosis and lower richness in tumor breast tissues compared to healthy adjacent paired tissue, within the same women
Breast cancer (BC) is the most common malignancy in women, in whom it reaches 20% of the total neoplasia incidence. Most BCs are considered sporadic and a number of factors, including familiarity, age, hormona...
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Article
Open AccessAccurate detection and quantification of SARS-CoV-2 genomic and subgenomic mRNAs by ddPCR and meta-transcriptomics analysis
SARS-CoV-2 replication requires the synthesis of a set of structural proteins expressed through discontinuous transcription of ten subgenomic mRNAs (sgmRNAs). Here, we have fine-tuned droplet digital PCR (ddPC...
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Article
Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth
The microbiota has been shown to promote intestinal tumourigenesis, but a possible anti-tumourigenic effect has also been postulated. Here, we demonstrate that changes in the microbiota and mucus composition a...
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Article
Open AccessNo metagenomic evidence of tumorigenic viruses in cancers from a selected cohort of immunosuppressed subjects
The possible existence of yet undiscovered human tumorigenic viruses is still under scrutiny. The development of large-scale sequencing technologies, coupled with bioinformatics techniques for the characteriza...
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Article
Open AccessManagement at the service of research: ReOmicS, a quality management system for omics sciences
Management and research represent a binomial almost unknown, whose potentialities and requirements have not yet been fully exploited even if, recently, the scientific and social communities have felt the burde...
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Article
Open AccessEnrichment of intestinal Lactobacillus by enhanced secretory IgA coating alters glucose homeostasis in P2rx7−/− mice
The secretory immunoglobulin A (SIgA) in mammalian gut protects the organism from infections and contributes to host physiology by sha** microbiota composition. The mechanisms regulating the adaptive SIgA re...
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Article
Open AccessDynamic inosinome profiles reveal novel patient stratification and gender-specific differences in glioblastoma
Adenosine-to-inosine (A-to-I) RNA editing is an essential post-transcriptional mechanism mediated by ADAR enzymes that have been recently associated with cancer.
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Article
Open AccessWhole transcriptome profiling of Late-Onset Alzheimer’s Disease patients provides insights into the molecular changes involved in the disease
Alzheimer’s Disease (AD) is the most common cause of dementia affecting the elderly population worldwide. We have performed a comprehensive transcriptome profiling of Late-Onset AD (LOAD) patients using second...
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Chapter and Conference Paper
Unbiased Taxonomic Annotation of Metagenomic Samples
The classification of reads from a metagenomic sample using a reference taxonomy is usually based on first map** the reads to the reference sequences and then, classifying each read at a node under the lowes...
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Article
Open AccessBioVeL: a virtual laboratory for data analysis and modelling in biodiversity science and ecology
Making forecasts about biodiversity and giving support to policy relies increasingly on large collections of data held electronically, and on substantial computational capability and capacity to analyse, model...
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Article
Open AccessBioMaS: a modular pipeline for Bioinformatic analysis of Metagenomic AmpliconS
Substantial advances in microbiology, molecular evolution and biodiversity have been carried out in recent years thanks to Metagenomics, which allows to unveil the composition and functions of mixed microbial ...
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Article
Open AccessThe influence of invasive jellyfish blooms on the aquatic microbiome in a coastal lagoon (Varano, SE Italy) detected by an Illumina-based deep sequencing strategy
The rapid expansion of multicellular native and alien species outbreaks in aquatic and terrestrial ecosystems (bioinvasions) may produce significant impacts on bacterial community dynamics and nutrient pathways w...
