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  1. Article

    Open Access

    Spatiotemporally resolved transcriptomics reveals the subcellular RNA kinetic landscape

    Spatiotemporal regulation of the cellular transcriptome is crucial for proper protein expression and cellular function. However, the intricate subcellular dynamics of RNA remain obscured due to the limitations...

    **gyi Ren, Haowen Zhou, Hu Zeng, Connie Kangni Wang, Jiahao Huang in Nature Methods (2023)

  2. No Access

    Protocol

    Node-Pore Sensing for Characterizing Cells and Extracellular Vesicles

    Node-Pore Sensing, NPS, is an extremely versatile and powerful technique for the analysis of cells and the detection of extracellular vesicles (EVs). NPS involves measuring the modulated current pulse caused b...

    Thomas Carey, Brian Li, Lydia L. Sohn in Biomedical Engineering Technologies (2022)

  3. Article

    Open Access

    Stress-induced tunneling nanotubes support treatment adaptation in prostate cancer

    Tunneling nanotubes (TNTs) are actin-based membranous structures bridging distant cells for intercellular communication. We define roles for TNTs in stress adaptation and treatment resistance in prostate cance...

    Alexander Kretschmer, Fan Zhang, Syam Prakash Somasekharan in Scientific Reports (2019)

  4. Article

    Open Access

    Droplet digital PCR shows the D-Loop to be an error prone locus for mitochondrial DNA copy number determination

    Absolute quantification of mitochondrial DNA copy number (mCN) provides important insights in many fields of research including cancer, cardiovascular and reproductive health. Droplet digital PCR (ddPCR) nativ...

    Brian Li, Sonal Kaushik, Pola Kalinowski, BaRun Kim, Cynthia Gershome in Scientific Reports (2018)

  5. No Access

    Chapter

    Learning from the Globalization of an Emerging Economy Firm: Are Current Internationalization Theories Relevant?

    Classic theories of firm globalization, including the Uppsala Internationalization Model (Johanson and Vahlne, 1977) and the Eclectic Paradigm (Dunning, 1973), were developed using data from firms originating ...

    Brian Li, Maya Kumar, Mary Ann Von Glinow in Experiences of Emerging Economy Firms (2015)

  6. No Access

    Chapter and Conference Paper

    Fast and Stable Interpolation of Well Data Using the Norm Function

    We present an iterative algorithm for computing an approximation to data in wells using the norm function in three dimensions augmented with a tensor product of two dimensional Lagrange functions with one dime...

    Brian Li, Jeremy Levesley in Approximation Algorithms for Complex Systems (2011)