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  1. Article

    Open Access

    Identifying and tracking mobile elements in evolving compost communities yields insights into the nanobiome

    Microbial evolution is driven by rapid changes in gene content mediated by horizontal gene transfer (HGT). While mobile genetic elements (MGEs) are important drivers of gene flux, the nanobiome—the zoo of Darw...

    Bram van Dijk, Pauline Buffard, Andrew D. Farr, Franz Giersdorf in ISME Communications (2023)

  2. Article

    Open Access

    Nutrition or nature: using elementary flux modes to disentangle the complex forces sha** prokaryote pan-genomes

    Microbial pan-genomes are shaped by a complex combination of stochastic and deterministic forces. Even closely related genomes exhibit extensive variation in their gene content. Understanding what drives this ...

    Daniel R. Garza, F. A. Bastiaan von Meijenfeldt, Bram van Dijk in BMC Ecology and Evolution (2022)

  3. Article

    Open Access

    Can mobile genetic elements rescue genes from extinction?

    Bacteria and other prokaryotes evolve primarily through rapid changes in their gene content by quickly losing and gaining genes whenever an ecological opportunity emerges. As gene loss and horizontal gene tran...

    Bram van Dijk in Current Genetics (2020)

  4. Article

    Open Access

    Contingent evolution of alternative metabolic network topologies determines whether cross-feeding evolves

    Metabolic exchange is widespread in natural microbial communities and an important driver of ecosystem structure and diversity, yet it remains unclear what determines whether microbes evolve division of labor ...

    Jeroen Meijer, Bram van Dijk, Paulien Hogeweg in Communications Biology (2020)

  5. Article

    Open Access

    Trusting the hand that feeds: microbes evolve to anticipate a serial transfer protocol as individuals or collectives

    Experimental evolution of microbes often involves a serial transfer protocol, where microbes are repeatedly diluted by transfer to a fresh medium, starting a new growth cycle. This has revealed that evolution ...

    Bram van Dijk, Jeroen Meijer, Thomas D. Cuypers in BMC Evolutionary Biology (2019)