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    CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing

    Alternative splicing of pre-messenger RNA is a key feature of transcriptome expansion in eukaryotic cells, yet its regulation is poorly understood. Spliceosome assembly occurs co-transcriptionally, raising the...

    Sanjeev Shukla, Ersen Kavak, Melissa Gregory, Masahiko Imashimizu… in Nature (2011)