-
Chapter and Conference Paper
Improving the Reduction Swelling Behavior of Fired Hematite Pellets by Increasing Basicity
Oxide pellets are widely regarded as high-quality raw materials for BF ironmaking and iron processes due to their excellent strength, performance and environmental properties. The decrease in the availabilit...
-
Article
Open AccessPipkin type III femoral head fracture: which treatment strategy can be recommended?
Pipkin type III femoral head fractures are relatively rare injuries. Few studies have explored and described the treatment and outcomes of Pipkin type III femoral head fractures. The purpose of this study was ...
-
Article
Open AccessDevelopment of a bispecific antibody targeting PD-L1 and TIGIT with optimal cytotoxicity
Programmed death-ligand 1 (PD-L1) and T cell immunoreceptor with Ig and ITIM domains (TIGIT) are two potential targets for cancer immunotherapy, early clinical studies showed the combination therapy of anti-PD...
-
Article
Open AccessNon-sampling errors in questionnaire surveys: findings from a National Fertility Survey
Non-sampling errors can generally be divided into three types: sampling frame errors, non-response errors and measurement errors. Missing target units in the sampling frame, improper handling of non-responses,...
-
Chapter and Conference Paper
Simple Fatigue Crack Propagation Evaluation by Enhanced Reference Stress Method Using Open-Source CAE
Although J-integral type fracture mechanics parameters are effective for estimating crack propagation behaviors under elastic–plastic situations such as low-cycle fatigue, calculation of J-integral type non-li...
-
Article
Open AccessEarly versus delayed hip reduction in the surgical treatment of femoral head fracture combined with posterior hip dislocation: a comparative study
Few studies focus on the treatment of femoral head fracture combined with posterior hip dislocation, and the safe interval time between injury and hip reduction remains controversial. The purpose of this study...
-
Article
Open AccessFertility intention and related factors in China: findings from the 2017 National Fertility Survey
This paper reports the fertility intension of women based on data from the national fertility survey in 2017 in China (CFS 2017), after implementation of the universal two-child policy, and analyses major rela...
-
Article
Open AccessFire needle acupuncture or moxibustion for chronic plaque psoriasis: study protocol for a randomized controlled trial
Psoriasis is a chronic, immune-mediated disorder with chronic plaque psoriasis being the primary manifestation during the remission stage. Patients often have a slow course and long history of the disease. The...
-
Article
Comparison of the modified Heuter approach and the Kocher-Langenbeck approach in the treatment of Pipkin type I and type II femoral head fractures
To evaluate and compare the effectiveness of the modified Heuter approach and the Kocher-Langenbeck approach in the treatment of Pipkin type I and II femoral head fractures.
-
Article
Open AccessTransarticular external fixation versus deltoid ligament repair in treating SER IV ankle fractures: a comparative study
The topic that whether the injured deltoid ligament should be repaired when associated with ankle joint fractures is still discussed. The objective of this study was to compare the clinical effect of open redu...
-
Article
Open AccessChina fertility survey 2017: design and implementation
This paper examines the design and the process used to carry out the China Fertility Survey 2017, a national representative survey that collected data on fertility desire, childbearing behavior, the use of chi...
-
Article
Open AccessRedirecting T cells to glypican-3 with 28.41BB.ζ and 28.ζ-41BBL CARs for hepatocellular carcinoma treatment
-
Article
Open AccessClinical analysis of peri-operative hidden blood loss of elderly patients with intertrochanteric fractures treated by unreamed proximal femoral nail anti-rotation
The purpose of this study was to quantify the peri-operative blood loss of elderly patients with intertrochanteric fractures treated by unreamed proximal femoral nail anti-rotation (PFNA) and analyze whether t...
-
Article
Open AccessIlizarov external fixation versus plate internal fixation in the treatment of end-stage ankle arthritis: decision analysis of clinical parameters
The purpose of this study was to evaluate the effect of Ilizarov external fixation (IEF) and plate internal fixation (PIF) in the treatment of end-stage ankle arthritis on pain relieving and function improveme...
-
Article
Open AccessOsteopontin facilitates tumor metastasis by regulating epithelial–mesenchymal plasticity
Tumor metastasis leads to high mortality; therefore, understanding the mechanisms that underlie tumor metastasis is crucial. Generally seen as a secretory protein, osteopontin (OPN) is involved in multifarious...
-
Article
Open AccessDownregulation of ASPP2 improves hepatocellular carcinoma cells survival via promoting BECN1-dependent autophagy initiation
Autophagy is an important catabolic process, which sustains intracellular homeostasis and lengthens cell survival under stress. Here we identify the ankyrin-repeat-containing, SH3-domain-containing, and prolin...
-
Article
Erratum to: A humanized anti-osteopontin antibody inhibits breast cancer growth and metastasis in vivo
-
Article
A humanized anti-osteopontin antibody inhibits breast cancer growth and metastasis in vivo
Osteopontin (OPN) has been implicated as an important mediator of breast cancer progression and metastasis and has been investigated for use as a potential therapeutic target in the treatment of breast cancer....
-
Article
PE38KDEL-loaded anti-HER2 nanoparticles inhibit breast tumor progression with reduced toxicity and immunogenicity
The clinical use of Pseudomonas exotoxin A (PE)-based immunotoxins is limited by the toxicity and immunogenicity of PE. To overcome the limitations, we have developed PE38KDEL-loaded poly(lactic-co-glycolic acid)...
-
Article
Treatment of hepatocellular carcinoma in a mouse xenograft model with an immunotoxin which is engineered to eliminate vascular leak syndrome
Vascular leak syndrome (VLS) is the major dose-limiting toxicity of immunotoxin and interleukin-2 therapy. It has been evidenced that VLS-inducing molecules share a three-amino acid consensus motif, (x)D(y), w...
