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Article
Exploiting genomic tools for genetic dissection and improving the resistance to Fusarium stalk rot in tropical maize
A stable genomic region conferring FSR resistance at ~250 Mb on chromosome 1 was identified by GWAS. Genomic prediction has the potential to improve FSR resistance.
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Article
Open AccessSustainable management of transboundary pests requires holistic and inclusive solutions
Globalization and changing climates are aggravating the occurrence and impacts of transboundary pests, and driving the emergence of new threats. Most of the low- and middle-income countries in Africa, Asia and...
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Article
Open AccessGenetic trends in CIMMYT’s tropical maize breeding pipelines
Fostering a culture of continuous improvement through regular monitoring of genetic trends in breeding pipelines is essential to improve efficiency and increase accountability. This is the first global study t...
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Article
Open AccessHost plant resistance for fall armyworm management in maize: relevance, status and prospects in Africa and Asia
Sustainable control of fall armyworm (FAW) requires implementation of effective integrated pest management (IPM) strategies, with host plant resistance as a key component. Significant opportunities exist for d...
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Article
Open AccessIdentification and fine map** of a major QTL (qRtsc8-1) conferring resistance to maize tar spot complex and validation of production markers in breeding lines
A major QTL of qRtsc8-1 conferring TSC resistance was identified and fine mapped to a 721 kb region on chromosome 8 at 81 Mb, and production markers were v...
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Article
Open AccessBeat the stress: breeding for climate resilience in maize for the tropical rainfed environments
Intensive public sector breeding efforts and public-private partnerships have led to the increase in genetic gains, and deployment of elite climate-resilient maize cultivars for the stress-prone environments ...
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Article
Open AccessGenetic dissection of Striga hermonthica (Del.) Benth. resistance via genome-wide association and genomic prediction in tropical maize germplasm
Genome-wide association revealed that resistance to Striga hermonthica is influenced by multiple genomic regions with moderate effects. It is possible to increase genetic gains from selection for Striga resistanc...
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Article
Open AccessMaximizing efficiency of genomic selection in CIMMYT’s tropical maize breeding program
Historical data from breeding programs can be efficiently used to improve genomic selection accuracy, especially when the training set is optimized to subset individuals most informative of the target testing ...
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Article
Open AccessApplications of genoty**-by-sequencing (GBS) in maize genetics and breeding
Genoty**-by-Sequencing (GBS) is a low-cost, high-throughput genoty** method that relies on restriction enzymes to reduce genome complexity. GBS is being widely used for various genetic and breeding applica...
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Article
Open AccessGenomic prediction across years in a maize doubled haploid breeding program to accelerate early-stage testcross testing
Genomic selection with a multiple-year training population dataset could accelerate early-stage testcross testing by skip** the first-stage yield testing, which significantly saves the time a...
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Article
Open AccessMolecular diversity and selective sweeps in maize inbred lines adapted to African highlands
Little is known on maize germplasm adapted to the African highland agro-ecologies. In this study, we analyzed high-density genoty** by sequencing (GBS) data of 298 African highland adapted maize inbred lines...
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Article
Open AccessGenetic architecture of maize chlorotic mottle virus and maize lethal necrosis through GWAS, linkage analysis and genomic prediction in tropical maize germplasm
Analysis of the genetic architecture of MCMV and MLN resistance in maize doubled-haploid populations revealed QTLs with major effects on chromosomes 3 and 6 that were consistent across genetic backgrounds and ...
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Article
Open AccessDiscovery and validation of genomic regions associated with resistance to maize lethal necrosis in four biparental populations
In sub-Saharan Africa, maize is the key determinant of food security for smallholder farmers. The sudden outbreak of maize lethal necrosis (MLN) disease is seriously threatening the maize production in the reg...
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Article
Marker-assisted introgression of opaque2 allele for rapid conversion of elite hybrids into quality protein maize
Maize is a valuable source of food and feed worldwide. Maize endosperm protein is, however nutritionally poor due to the reduced levels of two essential amino acids, lysine and tryptophan. In this study, reces...
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Article
Open AccessGenetic analysis of tropical maize inbred lines for resistance to maize lethal necrosis disease
Maize lethal necrosis (MLN) disease is a recent outbreak in eastern Africa and has emerged as a significant threat to maize production in the region. The disease is caused by the co-infection of Maize chloroti...
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Article
Open AccessGrain yield performance and flowering synchrony of CIMMYT’s tropical maize (Zea mays L.) parental inbred lines and single crosses
Maize production constraints in sub-Saharan Africa (SSA) are being addressed by CIMMYT and partners through an array of projects, focusing on develo** and evaluating parental inbred lines and single-crosses ...
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Article
Open AccessMolecular characterization of CIMMYT maize inbred lines with genoty**-by-sequencing SNPs
Molecular characterization information on genetic diversity, population structure and genetic relationships provided by this research will help maize breeders to better understand how to utiliz...
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Article
Open AccessPerformance and grain yield stability of maize populations developed using marker-assisted recurrent selection and pedigree selection procedures
A marker-assisted recurrent selection (MARS) program was undertaken in sub-Saharan Africa to improve grain yield under drought-stress in 10 biparental tropical maize populations. The objectives of the present ...
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Article
Open AccessGenome-wide association and genomic prediction of resistance to maize lethal necrosis disease in tropical maize germplasm
Genome-wide association analysis in tropical and subtropical maize germplasm revealed that MLND resistance is influenced by multiple genomic regions with sma...
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Article
Open AccessMolecular map** across three populations reveals a QTL hotspot region on chromosome 3 for secondary traits associated with drought tolerance in tropical maize
Identifying quantitative trait loci (QTL) of sizeable effects that are expressed in diverse genetic backgrounds across contrasting water regimes particularly for secondary traits can significantly complement t...