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Article
Open AccessCharacterization of immune checkpoints expression and lymphocyte densities of iranian breast cancer patients; the co-expression status and clinicopathological associates
Breast malignancies are now the most common and deadliest type of neoplasms among women worldwide. Novel therapeutic approaches are needed to combat advanced stages of breast cancer. In this study, we aimed to...
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Article
Rhabdomyosarcoma mimicking lymphoma
Rhabdomyosarcoma (RMS) is a malignant soft tissue tumor that accounts for approximately one-half of soft tissue sarcomas in childhood age groups. Metastatic RMS is a rare condition that occurs in less than 25%...
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Article
Open AccessPathogenic role of Twist-1 protein in hydatidiform molar pregnancies and investigation of its potential diagnostic utility in complete moles
Complete and partial moles (PM) are the most common gestational trophoblastic diseases. Due to some overlap** morphological findings, ancillary studies may be necessary.
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Article
Cushing syndrome secondary to a mediastinal carcinoid tumor: a case report
Neuroendocrine tumors (NET) are a rare and diverse set of malignancies that can develop anywhere within the body. ACTH-producing mediastinal NETs often originate from the thymus in the anterior mediastinum and...
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Article
Open AccessMCM6 versus Ki-67 in diagnosis of luminal molecular subtypes of breast cancers
Currently, breast cancers are divided into four major molecular subtypes. The distinction between the luminal A and luminal B subtypes is mainly based on the cellular proliferation indices and is assessed by t...
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Article
Primary thoracic gastrinoma causing Zollinger-Ellison syndrome
Gastrinomas are located largely in the pancreaticoduodenal region. However, gastrinomas have also been found in non-pancreaticoduodenal regions. Our study is a rare report of gastrinomas within the thoracic ca...
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Article
Open AccessAssociation between colorectal cancer and Fusobacterium nucleatum and Bacteroides fragilis bacteria in Iranian patients: a preliminary study
Recent studies have proposed that commensal bacteria might be involved in the development and progression of gastrointestinal disorders such as colorectal cancer (CRC). Therefore, in this study, the relative a...
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Article
Particulates induced lung inflammation and its consequences in the development of restrictive and obstructive lung diseases: a systematic review
Particulate matters (PMs) are significant components of air pollution in the urban environment. PMs with aerodynamic diameter less than 2.5 μm (PM2.5) can penetrate to the alveolar area and introduce numerous com...
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Breast Cytology and Pathology in Pregnancy and Lactation
Breast tissue reveals some physiologic changes during pregnancy and lactation due to hormonal alterations. Whole range of breast diseases including inflammatory, benign and malignant neoplasms can be seen in p...
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Histology of Pregnancy-Associated Breast Cancer
Breasts are one of the most common sites of neoplastic lesions in women during pregnancy and lactation. This chapter reviews carcinomas of the breast during pregnancy and lactation while focusing on histolo...
