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Chapter
Cancer
A number of lifestyle factors affect cancer risk and survival, including nutrition and eating patterns, overweight and obesity status, physical activity and sedentary behavior, and alcohol and tobacco use. Mor...
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Article
Future directions in cancer prevention
In the past three decades, the approach to cancer prevention has moved from population and epidemiological studies to molecular targeting and immunological app...
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Article
Oral low dose and topical tamoxifen for breast cancer prevention: modern approaches for an old drug
Tamoxifen is a drug that has been in worldwide use for the treatment of estrogen receptor (ER)-positive breast cancer for over 30 years; it has been used in both the metastatic and adjuvant settings. Tamoxifen...
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Chapter
Prostate Cancer Prevention and the Selenium and Vitamin E Cancer Prevention Trial (SELECT): A Selenium Perspective
The Selenium and Vitamin E Cancer Prevention Trial (SELECT) randomized 35,533 healthy men, ≥55 years (≥50 years if African American), with normal digital rectal exams and prostate-specific antigens <4 ng/mL, t...
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Article
Update on Phase I/II Breast Cancer Prevention Trials
The greatest success in breast cancer prevention has been with two agents, tamoxifen and raloxifene, both of which are approved by the US Food and Drug Administration (FDA) for the risk reduction of invasive b...
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Chapter
Biomarkers for Early Detection and as Surrogate Endpoints in Cancer Prevention Trials: Issues and Opportunities
In order to improve the early detection and diagnosis of cancer, give more accurate prognoses, stratify individuals by risk, predict response to treatment, and help the transition of basic research into clinic...
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Article
Health disparities in breast cancer: biology meets socioeconomic status
Breast cancer is the most common cancer in women worldwide, accounting for just over 1 million new cases annually. Population-based statistics show that globally, when compared to whites, women of African ance...
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Chapter and Conference Paper
Seleneium and Vitamin E Cancer Prevention Trial: A Nutrient Approach to Prostate Cancer Prevention
Prostate cancer continues to be both a major health threat, especially among African-American men, and a public health burden. However, growing evidence suggests that selenium and vitamin E may decrease the ri...
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Chapter and Conference Paper
Do We Make Optimal Use of the Potential of Cancer Prevention?
Abstract Three decades of intensive experimental and clinical research on cancer prevention have yielded an impressive body of scientific knowledge about cancer epidemiology, causation, and preventative measur...
