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  1. No Access

    Article

    White matter tract conductivity is resistant to wide variations in paranodal structure and myelin thickness accompanying the loss of Tyro3: an experimental and simulated analysis

    Myelination within the central nervous system (CNS) is crucial for the conduction of action potentials by neurons. Variation in compact myelin morphology and the structure of the paranode are hypothesised to h...

    Farrah Blades, Jordan D. Chambers, Timothy D. Aumann… in Brain Structure and Function (2022)

  2. No Access

    Article

    A drug-tunable Flt23k gene therapy for controlled intervention in retinal neovascularization

    Gene therapies that chronically suppress vascular endothelial growth factor (VEGF) represent a new approach for managing retinal vascular leakage and neovascularization. However, constitutive suppression of VE...

    **ying Chen, Fan-Li Lin, Jacqueline Y. K. Leung, Leilei Tu, Jiang-Hui Wang… in Angiogenesis (2021)

  3. No Access

    Article

    AAV-mediated gene delivery of the calreticulin anti-angiogenic domain inhibits ocular neovascularization

    Ocular neovascularization is a common pathological feature in diabetic retinopathy and neovascular age-related macular degeneration that can lead to severe vision loss. We evaluated the therapeutic efficacy of...

    Leilei Tu, Jiang-Hui Wang, Veluchamy A. Barathi, Selwyn M. Prea, Zheng He… in Angiogenesis (2018)