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Book
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Chapter
Perspectives
At the end of this book, one might have the impression of a gap between the current technical possibilities of investigation in child psychiatry and the actual findings. Most studies have been done on groups a...
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Chapter
Cerebral development and neurophysiological investigations
Most childhood psychiatric syndromes appear at a well defined stage of development (Fig. 1) which in part determines their clinical picture. Thus, autism appears very early and affects all adaptive functions: ...
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Chapter
Anatomical and physiological bases of the main electroencephalographic rhythms
The electroencephalogram (EEG), described for the first time by Berger (1929), was for a long time the only method available for functional exploration of the brain and was thus used for diagnostic purposes. A...
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Article
Validation of the Revised Behavior Summarized Evaluation Scale
The Behavioral Summarized Evaluation scale (BSE), previously published and validated, was developed for the evaluation of the autistic behavior in developmentally disordered children. A revised v...
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Article
Quantified multidimensional assessment of autism and other pervasive developmental disorders. Application for bioclinical research
A large number of investigation techniques are used to establish the relationships between the clinical and biological data which are necessary for physiopathological analysis in the field of developmental dis...
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Chapter and Conference Paper
Regional Cerebral Blood Flow and Auditory Evoked Potential Studies in Childhood Autism
An impairment of sensory modulation has been proposed as a putative brain dysfuntion in autism. All sensory modalities could be affected and the faulty modulation is manifest as either underreactivity or overr...
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Article
Autism and family home movies: Preliminary findings
Preliminary analyses of 12 home movies taken by parents before the recognition of autistic disorders of their own child confirm the major value of this method for describing early signs: anomalies of eye conta.....
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Article
Cortical evoked potentials as indicators of auditory-visual cross-modal association in young adults
Auditory evoked potentials (AEPs) were studied from scalp locations Cz and Oz on 37 adults aged 20–22 years during sensori-sensorial association of a weak sound (S) and a strong flash of light (L). After sound...
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Article
The behavioral summarized evaluation: Validity and reliability of a scale for the assessment of autistic behaviors
The Behavioral Summarized Evaluation (BSE), is a 20-item paper- and-pencil rating scale specifically designed for the measurement of behavioral parameters which could be related to biological data in autistic .....
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Chapter and Conference Paper
Monoaminergic Systems and Child Psychiatric Pathophysiology
Since the demonstration in 1921 by Otto Loewi that a chemical substance was released after nervous stimulation, much neuroscientific research has been performed on neurotransmission and chemical synapse. Work ...
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Chapter and Conference Paper
Clinical, Electrophysiological, and Biochemical Markers and Monoaminergic Hypotheses in Autism
Early infantile autism, originally described by Kanner (1943), is a syndrome defined by a set of clinical features including failure to develop normal social relationships, developmental disturbances of verbal...
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Chapter and Conference Paper
Sleep Disturbances in Children: From the Physiological to the Clinical
During childhood, more than one child in two has a sleep problem, ranging from a simple transitory episode such as nocturnal awakening to a genuine sleep disorder such as narcolepsy. Although there may exist a...
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Article
Urinary free and conjugated catecholamines and metabolites in autistic children
Urinary catecholamines (DA, NE, E) and their main metabolites (HVA, DOPAC, MHPG) were analyzed both as free and conjugates in eight children diagnosed as autistic according to DSM-III criteria and eight normal...
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Article
Auditory evoked responses and their modifications during conditioning paradigm in autistic children
Auditory evoked responses (AERs) were recorded from 16 autistic children (ages 2–10 years) and age-matched normal and retarded controls. In order to test the ability to form auditory-visual cross-modal associa.....
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Article
Dopamine-beta-hydroxylase (DBH) and homovanillic acid (HVA) in autistic children
In the present study, plasma DBH activity and urinary HVA levels were measured in 19 autistic and 15 normal children. DBH activity was significantly elevated in the 8 less retarded autistic patients. In this s.....
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Article
Effects of pyridoxine and magnesium on autistic symptoms—Initial observations
In an open trial, a heterogeneous group of 44 children with autistic symptoms were treated with large doses of vitamin B6 and magnesium. Clinical improvement with worsening on termination of the trial was observe...
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Chapter
Sensory Conditioning of Evoked Potentials in Chronic Alcoholics
Evoked potential (EP) studies have shown that alcoholism is associated with altered electrocortical activity. Begleiter et al. (1974) used the recovery cycle of somatosensory EPs, Their results indicated a pro...
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Chapter
Abstracts
