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Article
Tolerance Evaluation of L-asparaginase loaded in red blood cells
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Article
Improved pharmacodynamics of l-asparaginase-loaded in human red blood cells
To evaluate the modification of pharmacodynamic parameters induced by the administration of l-asparaginase loaded into red blood cells, 13 patients received a single dose of l-asparaginase internalised into the c...
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Chapter and Conference Paper
Monoaminergic Systems and Child Psychiatric Pathophysiology
Since the demonstration in 1921 by Otto Loewi that a chemical substance was released after nervous stimulation, much neuroscientific research has been performed on neurotransmission and chemical synapse. Work ...
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Chapter and Conference Paper
Clinical, Electrophysiological, and Biochemical Markers and Monoaminergic Hypotheses in Autism
Early infantile autism, originally described by Kanner (1943), is a syndrome defined by a set of clinical features including failure to develop normal social relationships, developmental disturbances of verbal...
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Article
Urinary dopamine metabolites as indicators of the responsiveness to fenfluramine treatment in children with autistic behavior
Modifications in serotonin and dopamine metabolism were evaluated in 13 children with autistic behavior and related to their responsiveness to fenfluramine treatment. A double-blind medication-placebo crossove...
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Chapter
Vascular Connective Matrices and Haemostasis in Diabetic Angiopathy
Diabetic angiopathy is characterized by two types of alterations. The first concerns glycoprotein metabolism: an increase in synthesis or a decrease in catabolism leads to the accumulation of “glycoprotein mat...
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Article
Urinary free and conjugated catecholamines and metabolites in autistic children
Urinary catecholamines (DA, NE, E) and their main metabolites (HVA, DOPAC, MHPG) were analyzed both as free and conjugates in eight children diagnosed as autistic according to DSM-III criteria and eight normal...
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Article
Dopamine-beta-hydroxylase (DBH) and homovanillic acid (HVA) in autistic children
In the present study, plasma DBH activity and urinary HVA levels were measured in 19 autistic and 15 normal children. DBH activity was significantly elevated in the 8 less retarded autistic patients. In this s.....
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Article
Effects of in vitroN-glucosylation on type-I collagen fibrillogenesis
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Article
Effects of pyridoxine and magnesium on autistic symptoms—Initial observations
In an open trial, a heterogeneous group of 44 children with autistic symptoms were treated with large doses of vitamin B6 and magnesium. Clinical improvement with worsening on termination of the trial was observe...
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Chapter
Abstracts
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Article
Isolement de glycoprotéides solubilisés par action de la collagénase sur la membrane basale glomérulaire humaine
Beitrag zur chemischen Zusammensetzung der Glykoproteine aus der glomerulären Basalmembran der Menschenniere.